Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | FGF1 | P05230 | 3/20 | 0.38 |
| ▸ | FGF2 | P09038 | 3/20 | 0.38 |
| ▸ | VEGFA | P15692 | 3/20 | 0.38 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673402 | 0.98 | GBA1 (0.47) | GBA1RECQLMAPK1GLAHPGD | |
| SCHEMBL9814204 | 0.98 | GBA1 (0.47) | GBA1RECQLMAPK1GLAHPGD | |
| SCHEMBL11847042 | 0.98 | GBA1 (0.47) | GBA1RECQLMAPK1GLAHPGD | |
| SCHEMBL4458651 | 0.93 | — | — | |
| SCHEMBL3125655 | 0.87 | LPAR2 (0.45) | — | |
| SCHEMBL7519409 | 0.82 | — | — | |
| SCHEMBL6574209 | 0.81 | GBA1 (0.46) | GBA1RECQLMAPK1GLAHPGD | |
| SCHEMBL6574204 | 0.81 | GBA1 (0.46) | GBA1RECQLMAPK1GLAHPGD | |
| SCHEMBL8992926 | 0.81 | GBA1 (0.46) | GBA1RECQLMAPK1GLAHPGD | |
| SCHEMBL18848257 | 0.79 | GBA1 (0.43) | GBA1MAPK1FGF1FGF2VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940928-A1 | HIGH MOBILITY LOW EMISSION SURFACTANTS FOR POLYURETHANE FOAMS | Momentive Performance Materials Inc. (US) | 2008-07-09 | — | — | EP | claimed |
| WO-2007037896-A1 | HIGH MOBILITY LOW EMISSION SURFACTANTS FOR POLYURETHANE FOAMS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2007-04-05 | — | — | WO | claimed |
| EP-0229947-B1 | NOVEL CRYSTALLINE SALTS OF ARYLOXY-PROPANOLAMINES, THEIR PREPARATION AND THEIR USE | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1991-03-13 | — | — | EP | claimed |
| EP-0248879-A4 | SYNTHESIS OF ARYLOXYPROPANOLAMINES AND ARYLETHANOLAMINES. | DU PONT (US) | 1990-02-26 | — | — | EP | claimed |
| EP-0248879-A1 | SYNTHESIS OF ARYLOXYPROPANOLAMINES AND ARYLETHANOLAMINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-16 | — | — | EP | claimed |
| WO-1987003583-A1 | SYNTHESIS OF ARYLOXYPROPANOLAMINES AND ARYLETHANOLAMINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-06-18 | — | — | WO | claimed |
| EP-0229947-A1 | Novel crystalline salts of aryloxy-propanolamines, their preparation and their use | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1987-07-29 | — | — | EP | disclosed |
| US-4139537-A | 3-Aryloxy-1-(2- or 4-iminodihydro-1-pyridyl)-2-propanol antiarrhythmic compounds | COOPER LABORATORIES, INC. (US) | 1979-02-13 | — | — | US | disclosed |