Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | FGF1 | P05230 | 3/20 | 0.40 |
| ▸ | FGF2 | P09038 | 3/20 | 0.40 |
| ▸ | VEGFA | P15692 | 3/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814204 | 1.00 | GBA1 (0.47) | GBA1RECQLMAPK1TSHRGLA | |
| SCHEMBL11847042 | 1.00 | GBA1 (0.47) | GBA1RECQLMAPK1TSHRGLA | |
| SCHEMBL4639776 | 0.98 | GBA1 (0.43) | GBA1RECQLMAPK1TSHRGLA | |
| SCHEMBL4458651 | 0.91 | — | — | |
| SCHEMBL3125655 | 0.89 | LPAR2 (0.45) | — | |
| SCHEMBL7519409 | 0.80 | — | — | |
| SCHEMBL8992926 | 0.79 | GBA1 (0.46) | GBA1RECQLMAPK1TSHRGLA | |
| SCHEMBL6574204 | 0.79 | GBA1 (0.46) | GBA1RECQLMAPK1TSHRGLA | |
| SCHEMBL6574209 | 0.79 | GBA1 (0.46) | GBA1RECQLMAPK1TSHRGLA | |
| SCHEMBL2784705 | 0.79 | GBA1 (0.55) | GBA1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037172-A2 | SELENIUM BROMIDE-OIL-EPICHLOROHYDRIN REACTION PRODUCTS | AVRAM ELENA (US) | 2004-05-06 | — | — | WO | disclosed |
| US-6632837-B1 | Compositions containing a selenium monobromide-oil reaction product and epichlorohydrin and methods of making the same | AVRAM ELENA (US) | 2003-10-14 | — | — | US | disclosed |