Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641227 | 0.96 | POLB (0.46) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL4639422 | 0.91 | SMN1; SMN2 (0.42) | POLBLMNAKDM4EUSP2MAPT | |
| SCHEMBL4640052 | 0.87 | KDM4E (0.46) | LMNAMAPK1KDM4EHSD17B10 | |
| SCHEMBL4641207 | 0.86 | KDM4E (0.43) | POLBLMNAMAPK1L3MBTL1KDM4E | |
| SCHEMBL4641238 | 0.85 | LMNA (0.41) | POLBLMNAKDM4EUSP2MAPT | |
| SCHEMBL4639814 | 0.85 | KDM4E (0.41) | POLBLMNAKDM4EUSP2MAPT | |
| SCHEMBL4639873 | 0.85 | LMNA (0.41) | POLBLMNAKDM4EUSP2MAPT | |
| SCHEMBL4641121 | 0.84 | KDM4E (0.42) | POLBLMNAKDM4EUSP2MAPT | |
| SCHEMBL4639483 | 0.84 | KDM4E (0.44) | LMNAMAPK1KDM4EUSP2MAPT | |
| SCHEMBL4639396 | 0.84 | SMN1; SMN2 (0.44) | POLBLMNAMAPK1KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954684-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007058338-A9 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007058338-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-05-24 | — | — | WO | disclosed |