Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641134 | 0.87 | TSHR (0.41) | KDM4EGAAMAPTALDH1A1ALOX15 | |
| SCHEMBL4639908 | 0.83 | ALDH1A1 (0.43) | KDM4EALDH1A1TSHRHSD17B10L3MBTL1 | |
| SCHEMBL4640044 | 0.83 | HMGB1 (0.45) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL4644056 | 0.81 | CYP3A4 (0.46) | KDM4EGAAMAPTALDH1A1HPGD | |
| SCHEMBL20139840 | 0.78 | KDM4E (0.42) | KDM4EGAAMAPTALDH1A1HPGD | |
| SCHEMBL29932867 | 0.78 | KDM4E (0.42) | KDM4EGAAMAPTALDH1A1HPGD | |
| SCHEMBL1228123 | 0.76 | CYP4A11 (0.47) | KDM4EGAAMAPTALDH1A1HPGD | |
| SCHEMBL27387385 | 0.76 | CFTR (0.53) | KDM4EMAPTCFTR | |
| SCHEMBL1229402 | 0.75 | MAPT (0.41) | KDM4EGAAMAPTALDH1A1HPGD | |
| SCHEMBL1228162 | 0.73 | ALDH1A1 (0.39) | KDM4EGAAMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120391-B1 | MOLECULAR COMPOUNDS CONTAINING NOVEL CARBOXYLIC ACID DERIVATIVES AS THE CONSTITUENT COMPOUND | NIPPON SODA CO (JP) | 2008-08-06 | — | — | EP | disclosed |
| US-6566548-B1 | Alkylene- or phenylene- tetrabenzoic acids and derivatives | NIPPON SODA CO., LTD. (JP) | 2003-05-20 | — | — | US | disclosed |
| EP-1120391-A1 | MOLECULAR COMPOUNDS CONTAINING NOVEL CARBOXYLIC ACID DERIVATIVES AS THE CONSTITUENT COMPOUND | NIPPON SODA CO., LTD. (JP) | 2001-08-01 | — | — | EP | disclosed |