Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200354 | 0.80 | CYP1A2 (0.40) | CYP1A2NR1H4EPHX2KMT2AAPEX1 | |
| SCHEMBL823157 | 0.79 | CYP1A2 (0.56) | CYP1A2KMT2AAPEX1KDM4ETAAR1 | |
| SCHEMBL2241498 | 0.77 | CYP1A2 (0.44) | CYP1A2NR1H4EPHX2KMT2AAPEX1 | |
| SCHEMBL823222 | 0.77 | CYP1A2 (0.44) | CYP1A2NR1H4EPHX2KMT2AAPEX1 | |
| SCHEMBL6076728 | 0.76 | POLB (0.54) | CYP1A2KMT2AKDM4EHTTMAPK1 | |
| SCHEMBL9875991 | 0.76 | CYP1A2 (0.56) | CYP1A2KMT2AAPEX1KDM4ETAAR1 | |
| SCHEMBL9293422 | 0.75 | CYP1A2 (0.50) | CYP1A2KMT2AAPEX1KDM4ETAAR1 | |
| SCHEMBL13593098 | 0.75 | KDM4E (0.43) | NR1H4EPHX2KMT2AAPEX1ADORA2A | |
| SCHEMBL1284802 | 0.74 | CA2 (0.51) | CYP1A2NR1H4EPHX2KMT2AAPEX1 | |
| SCHEMBL22283351 | 0.74 | CYP1A2 (0.48) | CYP1A2KMT2AAPEX1KDM4ETAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465019-B1 | Imaging members | XEROX CORP (US) | 2008-08-06 | — | — | EP | disclosed |
| US-7297458-B2 | Electrophotographic image receivers comprising flexible supporting substrates having electroconductive, charge control, generating, transfer multilayers, binders and optionally adhesives; photoreceptors | XEROX CORPORATION (US) | 2007-11-20 | — | — | US | disclosed |
| US-7223507-B2 | Imaging members | XEROX CORPORATION (US) | 2007-05-29 | — | — | US | disclosed |
| US-20050287454-A1 | Electrophotographic image receivers comprising flexible supporting substrates having electroconductive, charge control, generating, transfer multilayers, binders and optionally adhesives; photoreceptors | XEROX CORPORATION | 2005-12-29 | — | — | US | disclosed |
| US-20040197685-A1 | Imaging members | XEROX CORPORATION | 2004-10-07 | — | — | US | disclosed |
| EP-1465019-A2 | Imaging members | Xerox Corporation (US) | 2004-10-06 | — | — | EP | disclosed |