SCHEMBL823157

SCHEMBL823157

CCNC(=O)c1ccc(C(=O)O)c2c(C(=O)NCC)ccc(C(=O)O)c12

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.56
KMT2A Q03164 3/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
LMNA P02545 1/20 0.42
BRD4 O60885 3/20 0.42
APEX1 P27695 1/20 0.42
KDM4E B2RXH2 2/20 0.41
TAAR1 Q96RJ0 1/20 0.41
KDM4C Q9H3R0 1/20 0.41
HTT P42858 2/20 0.40
CXCR2 P25025 1/20 0.39
MAPK1 P28482 1/20 0.39
TSHR P16473 1/20 0.39
PIN1 Q13526 1/20 0.39
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22283351 0.93 CYP1A2 (0.48) CYP1A2KMT2AL3MBTL1LMNABRD4
SCHEMBL16351299 0.88 CYP1A2 (0.44) CYP1A2KMT2AL3MBTL1LMNABRD4
SCHEMBL12037901 0.87 CYP1A2 (0.42) CYP1A2KMT2AL3MBTL1LMNABRD4
SCHEMBL6076728 0.85 POLB (0.54) CYP1A2KMT2AL3MBTL1KDM4EHTT
SCHEMBL6075731 0.82 HTT (0.64) CYP1A2L3MBTL1LMNAHTTTSHR
SCHEMBL6075636 0.80 HTT (0.57) CYP1A2L3MBTL1LMNAHTTTSHR
SCHEMBL6268376 0.80 KMT2A (0.65) CYP1A2KMT2AL3MBTL1LMNABRD4
SCHEMBL9875991 0.80 CYP1A2 (0.56) CYP1A2KMT2AAPEX1KDM4ETAAR1
SCHEMBL4640241 0.79 CYP1A2 (0.50) CYP1A2KMT2AAPEX1KDM4ETAAR1
SCHEMBL9293422 0.79 CYP1A2 (0.50) CYP1A2KMT2ALMNAAPEX1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530270-B2 Methods of preparing semiconductive compositions and devices EASTMAN KODAK COMPANY (US) 2013-09-10 US disclosed
US-8411489-B2 Semiconducting devices and methods of preparing EASTMAN KODAK COMPANY (US) 2013-04-02 US disclosed
US-8314265-B2 Aromatic amic acids or amic esters and compositions EASTMAN KODAK COMPANY (US) 2012-11-20 US disclosed
US-20110295010-A1 AROMATIC AMIC ACID SALTS AND COMPOSITIONS FPC INC. 2011-12-01 US disclosed
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed
WO-2011137137-A1 SEMICONDUCTING ARTICLES EASTMAN KODAK COMPANY (US) 2011-11-03 WO disclosed
WO-2011137133-A2 SEMICONDUCTING DEVICES AND METHODS OF PREPARING EASTMAN KODAK COMPANY (US) 2011-11-03 WO disclosed
US-20110269966-A1 SEMICONDUCTING ARTICLES CITICORP NORTH AMERICA, INC., AS AGENT 2011-11-03 US disclosed
US-20110266523-A1 SEMICONDUCTING DEVICES AND METHODS OF PREPARING BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed
US-20110269265-A1 METHODS OF PREPARING SEMICONDUCTIVE COMPOSITIONS AND DEVICES KODAK REALTY INC. 2011-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295010-A1 AROMATIC AMIC ACID SALTS AND COMPOSITIONS DDC, MYOC, TNNC1 CYP1A2 679/4885KMT2A 1190/4885L3MBTL1 4555/4885
US-20110269966-A1 SEMICONDUCTING ARTICLES ALAD, PORCN, DDC CYP1A2 498/4885KMT2A 2050/4885L3MBTL1 3040/4885
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS DDC, AADAC, MYOC CYP1A2 155/4885KMT2A 1249/4885L3MBTL1 3774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.