SCHEMBL4640314

SCHEMBL4640314

CC(O)Oc1ccc(O)cc1O

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.43
MAOB P27338 1/20 0.42
CA12 O43570 3/20 0.42
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA7 P43166 3/20 0.42
CA9 Q16790 3/20 0.42
CA14 Q9ULX7 3/20 0.42
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
PDK2 Q15119 1/20 0.37
PDK4 Q16654 1/20 0.37
BACE1 P56817 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19433124 0.85 CA12 (0.47) TYRMAOBCA12CA1CA2
SCHEMBL109611 0.80 TSHR (0.45) CA1CA2ALOX15ALOX12
Hydrochloric Acid SCHEMBL9794557 0.79 CASP1 (0.44) CA1CA2ALOX15ALOX12
SCHEMBL19433119 0.79 TYR (0.40) TYRMAOBCA12CA1CA2
Water SCHEMBL9794576 0.79 TSHR (0.44) CA1CA2ALOX15ALOX12
SCHEMBL18780639 0.77 CA12 (0.45) MAOBCA12CA1CA2CA7
Hydrochloric Acid SCHEMBL9794552 0.77 CASP1 (0.42) CA1CA2ALOX15ALOX12
SCHEMBL8214859 0.77 TSHR (0.53) TYRCA12CA1CA2CA7
SCHEMBL9795689 0.76 MAOB (0.39) TYRMAOBCA12CA1CA2
SCHEMBL14819041 0.76 CA12 (0.44) MAOBCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459900-B2 Process for dyeing of keratinic fibres with 2,4-diamino-1,3-dimethoxybenzene in an acid medium and composition using this process OREAL (FR) 2002-08-28 EP claimed
US-6024769-A HAIR COLORS AND HAIR DYEING; RESISTANCE TO LIGHT, WASHINGS, PERSPIRATION AND ADVERSE WEATHER L'OREAL (FR) 2000-02-15 US claimed
US-5938792-A APPLYING TO KERATINOUS FIBERS UNDER BASIC CONDITIONS COMPOSITION COMPRISING AMINOINDOLE COUPLER, OXIDATION DYE PRECURSOR, OXIDIZING AGENT L'OREAL (FR) 1999-08-17 US claimed
EP-0663814-B1 PROCESS FOR DYEING KERATIN FIBRES USING AN ACID PH ALCOXYMETEPHENYLENEDIAMINE AND COMPOSITIONS THEREFOR OREAL (FR) 1999-04-28 EP claimed
US-5752982-A DYEING HAIR IN LIGHTFAST, WASHFAST COLORS L'OREAL (FR) 1998-05-19 US claimed
US-5683474-A HAIR DYES AND OXIDATION DYE PRECURSOR WITH OXIDIZERS L'OREAL (FR) 1997-11-04 US claimed
EP-0589952-B1 USE OF SUPLHUR METAAMINOPHENOLS FOR DYEING KERATINIC FIBRES, TINCTORIAL COMPOSITIONS AND NOVEL COMPOUNDS OREAL (FR) 1997-08-27 EP claimed
EP-0465340-B2 Keratinous fibres dyeing process with 4-hydroxyindol at acidic pH and compositions OREAL (FR) 1997-03-05 EP claimed
EP-0594811-B1 OXIDATION HAIR DYE BASED ON A CREAMY CARRIER AND PROCESS FOR DYEING HAIR WELLA AG (DE) 1996-06-12 EP claimed
EP-0591373-B1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD OREAL (FR) 1996-05-22 EP claimed
US-4754069-A PHENOLIC COUPLERS WELLA AKTIENGESELLSCHAFT (DE) 1988-06-28 US claimed
WO-1988004166-A1 HAIR DYEING OXIDISING AGENT AND PROCESS WITH 3-(2',2',2'-TRIFLUOROETHYL)AMINO-PHENOL DERIVATES AND NEW 3-(2',2',2'-TRIFLUOROETHYL)AMINO-PHENOL DERIVATES WELLA AKTIENGESELLSCHAFT (DE) 1988-06-16 WO claimed
US-4725282-A LOW VISCOSITY; STORAGE STABILITY WELLA AKTIENGESELLSCHAFT (DE) 1988-02-16 US claimed
EP-0166155-B1 2-ALKYLSULPHONYL-1,4-DIAMINOBENZENES, PROCESS FOR THEIR PREPARATION AND OXIDATIVE HAIR-DYEING COMPOSITIONS CONTAINING THESE COMPOUNDS Wella Aktiengesellschaft (DE) 1987-09-23 EP claimed
US-4692166-A OXIDATION COLOR DYES USED WITH DIAMINOBENZENES OR AMINO PHENOLS; MINIMIZATION OF RED HUE L'OREAL (FR) 1987-09-08 US claimed
WO-1986000303-A1 TWO-ALKYL-SULPHONYL-1,4-DIAMINOBENZENES, PREPARATION THEREOF AND UTILISATION THEREOF WELLA AKTIENGESELLSCHAFT (DE) 1986-01-16 WO claimed
WO-1986000223-A1 HAIR COLOURING AGENT BASED ON A LOW-VISCOSITY CARRIER WELLA AKTIENGESELLSCHAFT (DE) 1986-01-16 WO claimed
EP-0166155-A1 2-Alkylsulphonyl-1,4-diaminobenzenes, process for their preparation and oxidative hair-dyeing compositions containing these compounds Wella Aktiengesellschaft (DE) 1986-01-02 EP claimed
EP-0166100-A1 Oxidation hair-dyeing composition based on a low-viscosity carrier Wella Aktiengesellschaft (DE) 1986-01-02 EP claimed
US-4543425-A 1,3-Diamino-4-(2',2',2',-trifluoroethoxy)-benzene, method of producing the same, and hair coloring composition containing the same WELLA AG (DE) 1985-09-24 US claimed