SCHEMBL9795689

SCHEMBL9795689

CC(O)Oc1cc(O)ccc1N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.39
CA12 O43570 3/20 0.36
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA7 P43166 3/20 0.36
CA9 Q16790 3/20 0.36
CA14 Q9ULX7 3/20 0.36
ALDH1A1 P00352 6/20 0.35
CYP3A4 P08684 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
HSD17B10 Q99714 2/20 0.35
TSHR P16473 1/20 0.35
CHEK1 O14757 1/20 0.35
ADRB1 P08588 1/20 0.34
MIF P14174 1/20 0.34
HTR2A P28223 1/20 0.34
ADRA1A P35348 1/20 0.34
HTR2B P41595 1/20 0.34
CTSL P07711 1/20 0.34
CTSB P07858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4389134 0.86 MAOB (0.41) MAOBCA12CA1CA2CA7
SCHEMBL214546 0.82 ALDH1A1 (0.42) ALDH1A1CYP3A4TDP1HSD17B10TSHR
Hydrochloric Acid SCHEMBL5792316 0.81 ALDH1A1 (0.44) ALDH1A1CYP3A4TDP1HSD17B10TSHR
SCHEMBL3168309 0.77 GAA (0.35) ALDH1A1CYP3A4HSD17B10HIF1ATHRB
SCHEMBL3237615 0.76 ALDH1A1 (0.39) MAOBALDH1A1CYP3A4TDP1TSHR
SCHEMBL4640314 0.76 TYR (0.43) MAOBCA12CA1CA2CA7
SCHEMBL30380626 0.75 ALDH1A1 (0.61) MAOBALDH1A1CYP3A4TDP1HSD17B10
SCHEMBL282092 0.75 ALDH1A1 (0.61) MAOBALDH1A1CYP3A4TDP1HSD17B10
SCHEMBL17498442 0.74 CA14 (0.44) MAOBCA12CA1CA2CA7
SCHEMBL11024727 0.74 HTT (0.63) ALDH1A1CYP3A4TDP1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5032137-A Hair dye L'OREAL (FR) 1991-07-16 US disclosed
US-4979961-A p-phenylenediamines, process for preparation thereof, dyeing composition containing them and corresponding dyeing process L'OREAL (FR) 1990-12-25 US disclosed