Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14484639 | 0.86 | ALDH1A1 (0.45) | KMT2AATMCHEK2CA12CA1 | |
| SCHEMBL29966096 | 0.80 | KDM4E (0.54) | KMT2ACA1CA2RAB9AMAPT | |
| SCHEMBL2468448 | 0.80 | KDM4E (0.54) | KMT2ACA1CA2RAB9AMAPT | |
| SCHEMBL516293 | 0.79 | ABL1 (0.46) | KMT2AATMCA12CA1CA2 | |
| SCHEMBL4640347 | 0.78 | JAK2 (0.46) | KMT2ARAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL2104774 | 0.77 | PARP10 (0.56) | KMT2AMKNK1MKNK2CA12CA1 | |
| SCHEMBL9901975 | 0.76 | AKR1C2 (0.47) | KMT2AMKNK1MKNK2KDM4EJAK2 | |
| SCHEMBL28039268 | 0.76 | PARP10 (0.56) | KMT2AATMCHEK2ALDH1A1 | |
| SCHEMBL15544328 | 0.75 | DGAT1 (0.41) | KMT2AMAPTCASP1ALDH1A1 | |
| SCHEMBL4687865 | 0.75 | SMN1; SMN2 (0.44) | KMT2AMKNK1MKNK2CHEK2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964834-A1 | Sulphonyltryptophanols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-09-03 | — | — | EP | disclosed |
| EP-1956016-A1 | Bicyclic acyltryptophanols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-08-13 | — | — | EP | disclosed |