Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.59 |
| ▸ | HTR2A | P28223 | 4/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 4/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601849 | 0.88 | MPO (0.60) | GPR84HTR2AHTR1AHTR2CMPO | |
| SCHEMBL9263226 | 0.88 | GPR84 (0.63) | GPR84HTR2AHTR1AHTR2CMPO | |
| SCHEMBL12633102 | 0.84 | GPR84 (0.67) | GPR84HTR2AHTR1AHTR2CMPO | |
| SCHEMBL3003807 | 0.83 | GPR84 (0.54) | GPR84HTR2AHTR1AHTR2CMPO | |
| SCHEMBL3003809 | 0.83 | GPR84 (0.54) | GPR84HTR2AHTR1AHTR2CMPO | |
| SCHEMBL14663588 | 0.80 | GPR84 (0.69) | GPR84HTR2AHTR1AHTR2CMPO | |
| SCHEMBL5643971 | 0.79 | GPR84 (0.55) | GPR84HTR2AHTR1AHTR2CMPO | |
| SCHEMBL3009547 | 0.77 | GPR84 (0.46) | GPR84HTR2AHTR1AHTR2CMPO | |
| SCHEMBL31415125 | 0.76 | HTR2A (0.75) | GPR84HTR2AHTR1AHTR2CMPO | |
| SCHEMBL6846117 | 0.76 | GPR84 (0.73) | GPR84HTR2AHTR1AHTR2CMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1956016-A1 | Bicyclic acyltryptophanols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-08-13 | — | — | EP | disclosed |