SCHEMBL4640478

SCHEMBL4640478

CC1(C)C=Nc2ccc(C#N)cc21

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.36
KDM1A O60341 1/20 0.34
CYP2A6 P11509 2/20 0.33
PDK2 Q15119 1/20 0.33
ALDH1A1 P00352 1/20 0.33
OPRD1 P41143 1/20 0.33
NSD2 O96028 1/20 0.33
ABCB1 P08183 7/20 0.32
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
DRD2 P14416 2/20 0.32
DRD3 P35462 2/20 0.32
PNMT P11086 1/20 0.32
SRPK2 P78362 1/20 0.31
SRPK1 Q96SB4 1/20 0.31
PGR P06401 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL926543 0.73 SMN1; SMN2 (0.34) CYP2A6ALDH1A1
SCHEMBL11221972 0.70 ALDH1A1 (0.36) TRPA1KDM1ACYP2A6PDK2ALDH1A1
SCHEMBL3842790 0.68 PDK2 (0.35) PDK2ALDH1A1PGR
SCHEMBL16905572 0.67 CYP2A6 (0.39) KDM1ACYP2A6PDK2ALDH1A1OPRD1
SCHEMBL29639106 0.66 HTR5A (0.35) PDK2
SCHEMBL22938361 0.66 MEN1 (0.40)
Hydrochloric Acid SCHEMBL30881482 0.65 HTR5A (0.34)
Iodide SCHEMBL29258426 0.65 HTR5A (0.37)
SCHEMBL16905204 0.64 KDM1A (0.44) KDM1ACYP2A6PDK2ALDH1A1OPRD1
SCHEMBL2223445 0.64 RARB (0.53) KDM1ANSD2DRD2DRD3PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0271260-B1 Supersensitization of silver halide emulsions MINNESOTA MINING & MFG (US) 1995-01-04 EP claimed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 US claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP claimed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed
EP-1298490-B1 Photopolymerizable composition and recording material FUJIFILM CORP (JP) 2008-08-13 EP disclosed
CN-101124516-A Pattern forming material, pattern forming apparatus, and pattern forming method FUJI FILM CORP (JP) 2008-02-13 CN disclosed
US-6828088-B2 Contrast and sensitivity FUJI PHOTO FILM CO., LTD. (JP) 2004-12-07 US disclosed
US-6756177-B2 MULTICOLOR RECORDING FUJI PHOTO FILM CO., LTD. (JP) 2004-06-29 US disclosed
US-6740466-B1 HIGH SENSITIVITY TO UV, VISIBLE, ANDINFRARED; FOGGING OF THE BACKGROUND IS REDUCED; CLARITY AND HIGH CONTRAST; ADDITION POLYMERIZABLE COMPOUND, AN INDOLE-PYRIMIDINETRIONE METHINE DYE, AN ANIONIC ORGANOBORON COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 2004-05-25 US disclosed
US-20040048207-A1 Silver halide photographic light-sensitive material FUJIFILM CORPORATION (JP) 2004-03-11 US disclosed
US-20030129521-A1 Photopolymerizable composition and recording material FUJI PHOTO FILM CO., LTD. 2003-07-10 US disclosed
EP-1315031-A2 Silver halide photographic light-sensitive material Fuji Photo Film Co. Ltd. (JP) 2003-05-28 EP disclosed
US-4138266-A SULFO-SUBSTITUTED CYANINE AND RED SHIFT TRIAZOLE DYES FUJI PHOTO FILM CO., LTD. (JP) 1979-02-06 US disclosed
US-4105454-A BENZOTRIAZOLE COMPOUND WHICH CAN PRODUCE SLIGHTLY SOLUBLE SILVER SALT FUJI PHOTO FILM CO., LTD. (JP) 1978-08-08 US disclosed
US-4046572-A SILVER HALIDE PHOTOGRAPHIC LIGHT SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JA) 1977-09-06 US disclosed
US-4002480-A CONTAINING A DINUCLEAR MEROCYANINE SENSITIZING DYE AND AN ANTIFOGGING AGENT FUJI PHOTO FILM CO., LTD. (JA) 1977-01-11 US disclosed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US disclosed
US-3955996-A Method for spectrally sensitizing photographic light-sensitive emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-05-11 US disclosed
US-3953215-A X-RAY FILM FUJI PHOTO FILM CO., LTD. (JA) 1976-04-27 US disclosed
US-3951666-A CYANINE AND MEROCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-04-20 US disclosed