Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | HTR2C | P28335 | 3/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.50 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.50 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.50 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.50 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.50 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.50 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.50 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.50 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14099188 | 0.92 | KMT2A (0.65) | KMT2ATDP1ABCB1HTR1AHTR2C | |
| SCHEMBL4640429 | 0.84 | HTR1A (0.64) | KMT2AABCB1HTR1AHTR2CHTR2A | |
| SCHEMBL4640421 | 0.84 | KMT2A (0.56) | KMT2AABCB1HTR1AHTR2CHTR2A | |
| SCHEMBL4640388 | 0.81 | METAP2 (0.55) | KMT2AABCB1HTR1AHTR2CPSMB11 | |
| SCHEMBL4641556 | 0.80 | KDM4E (0.62) | KMT2AABCB1HTR1AHTR2CHTR2A | |
| SCHEMBL4641710 | 0.79 | KMT2A (0.56) | KMT2AABCB1HTR1AHTR2CPSMB11 | |
| SCHEMBL4640430 | 0.79 | KMT2A (0.56) | KMT2AABCB1HTR1AHTR2CPSMB11 | |
| SCHEMBL4643756 | 0.79 | KMT2A (0.56) | KMT2AABCB1HTR1AHTR2CPSMB11 | |
| SCHEMBL10532931 | 0.79 | HTR1A (0.65) | KMT2AABCB1HTR1AHTR2CHTR2A | |
| SCHEMBL10532933 | 0.79 | HTR1A (0.65) | KMT2AABCB1HTR1AHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934924-B1 | NOVEL DIAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-6576642-B2 | Inhibitors of the production of Ig E antibodies, antiallergens | KOWA CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| US-20010039279-A1 | Diamide compounds and compositions containing the same | KOWA CO., LTD. (JP) | 2001-11-08 | — | — | US | disclosed |
| US-6297283-B1 | EXCELLENT INHIBITORY EFFECT ON THE PRODUCTION OF AN IGE ANTIBODY AND ARE HENCE USEFUL AS ANTIALLERGIC AGENTS | KOWA CO., LTD. (JP) | 2001-10-02 | — | — | US | disclosed |
| EP-0934924-A1 | NOVEL DIAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010039279-A1 | Diamide compounds and compositions containing the same | HRH4, HRH2, HRH1 | KMT2A 843/4885TDP1 3639/4885ABCB1 257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.