Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 1.00 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PI4KA | P42356 | 1/20 | 0.52 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.52 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398384 | 1.00 | ADORA2A (1.00) | ADORA2AGRM4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL31022155 | 0.98 | ADORA2A (0.96) | ADORA2AGRM4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL15815414 | 0.96 | ADORA2A (0.92) | ADORA2AGRM4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL29986426 | 0.96 | ADORA2A (0.92) | ADORA2AGRM4PIK3CDPIK3CAPIK3CB | |
| Formaldehyde SCHEMBL28253268 | 0.94 | ADORA2A (0.89) | ADORA2AGRM4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL24184593 | 0.89 | ADORA2A (0.79) | ADORA2AGRM4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL20233979 | 0.89 | ADORA2A (0.79) | ADORA2AGRM4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL15811022 | 0.88 | ADORA2A (0.79) | ADORA2AGRM4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL24596492 | 0.87 | ADORA2A (0.76) | ADORA2AGRM4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL3075421 | 0.86 | ADORA2A (0.75) | ADORA2AGRM4LMNAHTTPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4200310-B1 | SPIRO-CYCLOMETALATED IRIDIUM EMITTERS FOR OLED APPLICATIONS | UNIV HONG KONG (CN) | 2025-11-05 | — | — | EP | claimed |
| US-20250311689-A1 | SEEDLING GERMINATION AND GROWTH CONDITIONS | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2025-10-09 | — | — | US | claimed |
| CN-118459506-A | Iridium complex capable of preparing efficient device by using 4-pyrimidine formic acid as auxiliary ligand in solution | 云南师范大学 | 2024-08-09 | — | — | CN | claimed |
| US-20230357294-A1 | SPIRO-CYCLOMETALATED IRIDIUM EMITTERS FOR OLED APPLICATIONS | THE UNIVERSITY OF HONG KONG (HK) | 2023-11-09 | — | — | US | claimed |
| CN-116377458-A | Method for electrochemically synthesizing quinazoline derivative | 安徽科技学院 | 2023-07-04 | — | — | CN | claimed |
| CN-116157490-A | Spiro metallized iridium emitters for OLED applications | 香港大学 | 2023-05-23 | — | — | CN | claimed |
| WO-2023056236-A1 | SEEDLING GERMINATION AND GROWTH CONDITIONS | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2023-04-06 | — | — | WO | claimed |
| WO-2022037613-A1 | SPIRO-CYCLOMETALATED IRIDIUM EMITTERS FOR OLED APPLICATIONS | THE UNIVERSITY OF HONG KONG (CN) | 2022-02-24 | — | — | WO | claimed |
| CN-107698522-A | The preparation method of the phenylquinazoline of 6 chlorine, 3 amino, 3,4 dihydro, 4 hydroxyl 4 | 华中药业股份有限公司 | 2018-02-16 | — | — | CN | claimed |
| CN-106632086-A | 2-(2-iodoaryl)quinazoline compound and preparation method thereof | 江西省林业科学院 | 2017-05-10 | — | — | CN | claimed |
| US-9273012-B2 | Facile preparation of 4-substituted quinazolines and related heterocycles | UNIVERSITY OF HOUSTON SYSTEM (US) | 2016-03-01 | — | — | US | claimed |
| WO-2013050527-A1 | QUINAZOLINE DERIVATIVES AS PDE10A ENZYME INHIBITORS | H. LUNDBECK A/S (DK) | 2013-04-11 | — | — | WO | claimed |
| US-20080217582-A1 | CLASS OF LUMINESCENT IRIDIUM(III) COMPLEXES WITH 2-(DIPHENYLPHOSPHINO)PHENOLATE LIGAND AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF | CHI, YUN (TW) | 2008-09-11 | — | — | US | claimed |
| EP-1954782-A1 | ELECTROLUMINESCENT DEVICE WITH QUINAZOLINE COMPLEX EMITTER | EASTMAN KODAK COMPANY (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007064479-A1 | ELECTROLUMINESCENT DEVICE WITH QUINAZOLINE COMPLEX EMITTER | EASTMAN KODAK COMPANY (US) | 2007-06-07 | — | — | WO | claimed |
| US-20070122655-A1 | Electroluminescent device with quinazoline complex emitter | EASTMAN KODAK COMPANY | 2007-05-31 | — | — | US | claimed |
| EP-0079810-B1 | DERIVATIVES OF 4-PHENYL-QUINAZOLINE ACTIVE ON THE CENTRAL NERVOUS SYSTEM | SANOFI S.A. (FR) | 1986-01-22 | — | — | EP | claimed |
| US-4499092-A | ANTIEPILEPTIC AGENTS | SANOFI (FR) | 1985-02-12 | — | — | US | claimed |
| EP-4200310-B1 | SPIRO-CYCLOMETALATED IRIDIUM EMITTERS FOR OLED APPLICATIONS | UNIV HONG KONG (CN) | 2025-11-05 | — | — | EP | disclosed |
| US-4175964-A | SUCCESSIVE SURFACE TREATMENT WITH AQUEOUS SOLUTIONS OF PHOSPHORIC ACID AND SILICIC ACID OR ITS SALTS | FUJI PHOTO FILM CO., LTD. (JP) | 1979-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357294-A1 | SPIRO-CYCLOMETALATED IRIDIUM EMITTERS FOR OLED APPLICATIONS | TALDO1, SRD5A1, SRD5A2 | ADORA2A 2436/4885GRM4 3389/4885PIK3CD 2872/4885 |
| US-20080217582-A1 | CLASS OF LUMINESCENT IRIDIUM(III) COMPLEXES WITH 2-(DIPHENYLPHOSPHINO)PHENOLATE LIGAND AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF | IK, ITPR3, ITPR2 | ADORA2A 3857/4885GRM4 2029/4885PIK3CD 596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.