Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639606 | 0.90 | ESR1 (0.41) | ESR1LTA4H | |
| SCHEMBL4640167 | 0.89 | ESR1 (0.57) | ESR1 | |
| SCHEMBL6152326 | 0.86 | CYP19A1 (0.51) | ESR1 | |
| SCHEMBL4912016 | 0.85 | ESR1 (0.51) | ESR1LTA4H | |
| SCHEMBL4639556 | 0.85 | ESR1 (0.42) | ESR1LTA4H | |
| SCHEMBL4639760 | 0.84 | ESR1 (0.45) | ESR1LTA4H | |
| SCHEMBL4639650 | 0.82 | ESR1 (0.42) | ESR1LTA4HVKORC1 | |
| SCHEMBL6152270 | 0.79 | ESR1 (0.47) | ESR1 | |
| SCHEMBL4641971 | 0.77 | ESR1 (0.59) | ESR1LTA4H | |
| SCHEMBL6152455 | 0.76 | CYP19A1 (0.44) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667999-A4 | BENZOPYRANONE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARM LLC (US) | 2008-08-06 | — | — | EP | disclosed |
| EP-1667999-A1 | BENZOPYRANONE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | Signal Pharmaceuticals LLC (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005028472-A1 | BENZOPYRANONE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARMACEUTICALS, LLC (US) | 2005-03-31 | — | — | WO | disclosed |