Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 5/20 | 0.72 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.72 |
| ▸ | RAB9A | P51151 | 9/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.59 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | IGF1R | P08069 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15256286 | 0.86 | PDGFRB (0.66) | PDGFRBPDGFRARAB9AKMT2AMEN1 | |
| SCHEMBL1401415 | 0.84 | PDGFRB (1.00) | PDGFRBPDGFRARAB9AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL3884102 | 0.82 | PDGFRB (0.97) | PDGFRBPDGFRARAB9AKMT2AMEN1 | |
| SCHEMBL8610333 | 0.81 | PDGFRB (1.00) | PDGFRBPDGFRARAB9AKMT2AMEN1 | |
| SCHEMBL1702887 | 0.81 | PDGFRB (0.62) | PDGFRBPDGFRARAB9AKMT2AMEN1 | |
| SCHEMBL31098987 | 0.79 | RAB9A (0.61) | PDGFRBPDGFRARAB9AKMT2AMEN1 | |
| SCHEMBL1702586 | 0.79 | RAB9A (0.61) | PDGFRBPDGFRARAB9AKMT2AMEN1 | |
| SCHEMBL27839336 | 0.79 | PDGFRB (0.80) | PDGFRBPDGFRARAB9AKMT2AMEN1 | |
| SCHEMBL6213413 | 0.79 | PDGFRB (0.74) | PDGFRBPDGFRARAB9AKMT2AMEN1 | |
| SCHEMBL16388913 | 0.79 | PDGFRB (0.59) | PDGFRBPDGFRARAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1267819-B1 | Quinoxaline derivatives, compositions containing them und use as UV-filter | MERCK PATENT GMBH (DE) | 2008-08-06 | — | — | EP | claimed |
| US-20030207886-A1 | Preparation containing quinoxaline derivatives | MERCK PATENT GMBH (DE) | 2003-11-06 | — | — | US | claimed |
| EP-1267819-A2 | PREPARATION CONTAINING QUINOXALINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-01-02 | — | — | EP | claimed |
| WO-2001068047-A2 | PREPARATION CONTAINING QUINOXALINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2001-09-20 | — | — | WO | claimed |
| EP-1267819-B1 | Quinoxaline derivatives, compositions containing them und use as UV-filter | MERCK PATENT GMBH (DE) | 2008-08-06 | — | — | EP | disclosed |
| EP-1267819-B1 | Quinoxaline derivatives, compositions containing them und use as UV-filter | MERCK PATENT GMBH (DE) | 2008-08-06 | — | — | EP | disclosed |
| US-20030207886-A1 | Preparation containing quinoxaline derivatives | MERCK PATENT GMBH (DE) | 2003-11-06 | — | — | US | disclosed |
| EP-1267819-A2 | PREPARATION CONTAINING QUINOXALINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001068047-A2 | PREPARATION CONTAINING QUINOXALINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2001-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207886-A1 | Preparation containing quinoxaline derivatives | CUTA, XPA, NQO2 | PDGFRB 4344/4885PDGFRA 4218/4885RAB9A 989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.