Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SELL | P14151 | 1/20 | 0.41 |
| ▸ | SELP | P16109 | 1/20 | 0.41 |
| ▸ | SELE | P16581 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619006 | 0.82 | KMT2A (0.54) | KMT2AMEN1ALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL14677603 | 0.73 | KMT2A (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9447445 | 0.73 | CNR1 (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL11363822 | 0.73 | MEN1 (0.50) | KMT2AMEN1GAAHPGDL3MBTL1 | |
| SCHEMBL4776740 | 0.73 | SLC6A2 (0.47) | KMT2AMEN1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL9701512 | 0.73 | L3MBTL1 (0.45) | KMT2AMEN1L3MBTL1TDP1CYP2D6 | |
| SCHEMBL11388942 | 0.72 | SRC (0.54) | KMT2AMEN1CHRM1GAAL3MBTL1 | |
| SCHEMBL31413333 | 0.72 | KMT2A (0.57) | KMT2AMEN1ALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL3630774 | 0.72 | ACP3 (0.53) | KMT2AMEN1ALDH1A1GAAHPGD | |
| SCHEMBL27965885 | 0.71 | TYR (0.59) | KMT2AMEN1ALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888525-A1 | 3,6-DISUBSTITUTED AZABICYCLO [3.1.0]HEXANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006117754-A1 | 3,6-DISUBSTITUTED AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |