SCHEMBL4641670

SCHEMBL4641670

CCOC(=O)C=CC(=O)OCCCCC(=O)O[Si](CC)(CC)CC

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.47
HCAR2 Q8TDS4 5/20 0.45
MAPT P10636 2/20 0.41
RAB9A P51151 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
PRSS3 P35030 1/20 0.35
DGKA P23743 1/20 0.35
CYP1A2 P05177 1/20 0.35
TSHR P16473 3/20 0.34
HPGD P15428 1/20 0.34
ALDH1A1 P00352 3/20 0.34
CYP3A4 P08684 2/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4641658 1.00 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4645298 1.00 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4642341 0.95 ATM (0.49) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4645104 0.95 ATM (0.49) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4642329 0.95 ATM (0.49) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4642397 0.89 HCAR2 (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4642097 0.89 HCAR2 (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4642111 0.89 HCAR2 (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4641918 0.81 ATM (0.59) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4644233 0.81 ATM (0.50) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed