SCHEMBL4645104

SCHEMBL4645104

CCOC(=O)/C=C/C(=O)OCCCC(=O)O[Si](CC)(CC)CC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.49
HCAR2 Q8TDS4 5/20 0.44
MAPT P10636 5/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CYP1A2 P05177 1/20 0.36
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
LMNA P02545 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
NR1I2 O75469 1/20 0.33
PGR P06401 1/20 0.33
ADORA3 P0DMS8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642329 1.00 ATM (0.49) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4642341 1.00 ATM (0.49) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4641658 0.95 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4645298 0.95 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4641670 0.95 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4642397 0.90 HCAR2 (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4642111 0.90 HCAR2 (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4642097 0.90 HCAR2 (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4643586 0.80 HCAR2 (0.50) ATMHCAR2MAPTNPSR1ALDH1A1
SCHEMBL4646701 0.80 HCAR2 (0.50) ATMHCAR2MAPTNPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed