Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2208504 | 0.85 | TRPV1 (0.46) | TRPV1 | |
| SCHEMBL4641240 | 0.84 | TRPV1 (0.36) | TRPV1 | |
| SCHEMBL4619905 | 0.71 | GPR119 (0.34) | TRPV1EPHX2 | |
| SCHEMBL4619727 | 0.71 | ATM (0.36) | — | |
| SCHEMBL3246360 | 0.70 | TRPV1 (0.63) | TRPV1 | |
| SCHEMBL4028212 | 0.69 | TRPV1 (0.65) | TRPV1 | |
| SCHEMBL4620657 | 0.69 | TRPV1 (0.40) | TRPV1 | |
| SCHEMBL4024752 | 0.69 | TRPV1 (0.60) | TRPV1 | |
| SCHEMBL2205856 | 0.69 | TRPV1 (0.43) | TRPV1 | |
| SCHEMBL618043 | 0.68 | TRPV1 (0.59) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888542-A1 | SUBSTITUTED SPIRO-COMPOUNDS AND THE USE THEREOF FOR PRODUCING MEDICAMENTS | Grünenthal GmbH (DE) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006136245-A1 | SUBSTITUTED SPIRO-COMPOUNDS AND THE USE THEREOF FOR PRODUCING MEDICAMENTS | Grünenthal GmbH (DE) | 2006-12-28 | — | — | WO | disclosed |