Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 13/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619905 | 0.88 | GPR119 (0.34) | TRPV1GPR119 | |
| SCHEMBL2206230 | 0.85 | GPR119 (0.44) | TRPV1OPRM1GPR119 | |
| SCHEMBL4619379 | 0.80 | GPR119 (0.34) | GPR119 | |
| SCHEMBL4619951 | 0.79 | EPHX2 (0.41) | TRPV1 | |
| SCHEMBL4620004 | 0.79 | EPHX2 (0.41) | TRPV1 | |
| SCHEMBL4619894 | 0.79 | FAAH (0.39) | — | |
| SCHEMBL2204894 | 0.78 | GPR119 (0.42) | TRPV1GPR119 | |
| SCHEMBL4346000 | 0.77 | GPR119 (0.41) | TRPV1OPRM1GPR119 | |
| SCHEMBL4621118 | 0.76 | TRPV1 (0.46) | TRPV1 | |
| SCHEMBL2207528 | 0.75 | TRPV1 (0.47) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888542-A1 | SUBSTITUTED SPIRO-COMPOUNDS AND THE USE THEREOF FOR PRODUCING MEDICAMENTS | Grünenthal GmbH (DE) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006136245-A1 | SUBSTITUTED SPIRO-COMPOUNDS AND THE USE THEREOF FOR PRODUCING MEDICAMENTS | Grünenthal GmbH (DE) | 2006-12-28 | — | — | WO | disclosed |