Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4644809 | 0.96 | TDP1 (0.43) | TDP1ALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL4641814 | 0.91 | TDP1 (0.46) | TDP1ALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL4646842 | 0.89 | TDP1 (0.44) | TDP1ALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL4645456 | 0.87 | TDP1 (0.43) | TDP1ALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL4641806 | 0.87 | TDP1 (0.43) | TDP1ALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL4647220 | 0.85 | TDP1 (0.49) | TDP1ALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL4643648 | 0.85 | CA12 (0.50) | ALDH1A1MAPTKMT2AHSD17B10LMNA | |
| SCHEMBL4642055 | 0.85 | TDP1 (0.44) | TDP1ALDH1A1HSD17B10TP53NPC1 | |
| SCHEMBL4641715 | 0.84 | TDP1 (0.45) | TDP1ALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL4642607 | 0.82 | MTNR1A (0.48) | TDP1ALDH1A1MAPTKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487928-B1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2008-08-13 | — | — | EP | disclosed |
| EP-1487928-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | Jotun AS (NO) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080747-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2003-10-02 | — | — | WO | disclosed |