SCHEMBL4642607

SCHEMBL4642607

COc1ccc(Cl)c(OC(=O)CCl)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.48
MTNR1B P49286 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
TOP2A P11388 1/20 0.45
ALDH1A1 P00352 2/20 0.43
TUBB4A P04350 1/20 0.43
TUBB P07437 1/20 0.43
TUBA3C P0DPH7 1/20 0.43
TUBA1B P68363 1/20 0.43
TUBA4A P68366 1/20 0.43
TUBB4B P68371 1/20 0.43
TUBB3 Q13509 1/20 0.43
TUBB2A Q13885 1/20 0.43
TUBB8 Q3ZCM7 1/20 0.43
TUBA3E Q6PEY2 1/20 0.43
TUBA1A Q71U36 1/20 0.43
TUBA1C Q9BQE3 1/20 0.43
TUBB6 Q9BUF5 1/20 0.43
TUBB2B Q9BVA1 1/20 0.43
TUBB1 Q9H4B7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4647220 0.88 TDP1 (0.49) TDP1TOP2AALDH1A1MAPTTP53
SCHEMBL4642055 0.87 TDP1 (0.44) TDP1ALDH1A1TP53RAB9AHSD17B10
SCHEMBL4644298 0.86 TDP1 (0.43) TDP1ALDH1A1TP53HSD17B10NPC1
SCHEMBL4647806 0.85 TUBB4A (0.57) MTNR1AMTNR1BTOP2AALDH1A1TUBB4A
SCHEMBL4644720 0.85 TOP2A (0.59) MTNR1AMTNR1BTOP2AALDH1A1TUBB4A
SCHEMBL4646842 0.85 TDP1 (0.44) MTNR1AMTNR1BTDP1ALDH1A1MAPT
SCHEMBL4641814 0.84 TDP1 (0.46) TDP1ALDH1A1MAPTTP53LMNA
SCHEMBL4641806 0.84 TDP1 (0.43) TDP1ALDH1A1MAPTTP53MEN1
SCHEMBL4641715 0.83 TDP1 (0.45) TDP1ALDH1A1MAPTTP53LMNA
SCHEMBL4641848 0.82 TDP1 (0.44) TDP1ALDH1A1MAPTTP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed