SCHEMBL4642041

SCHEMBL4642041

[CH2]C(=O)OC(=O)C(Cl)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.41
CYP2D6 P10635 3/20 0.39
SRC P12931 2/20 0.39
MEN1 O00255 1/20 0.38
TSHR P16473 1/20 0.38
CYP1A2 P05177 2/20 0.38
PKM P14618 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
LMNA P02545 4/20 0.38
CHRM2 P08172 2/20 0.38
CHRM4 P08173 2/20 0.38
CHRM1 P11229 2/20 0.38
CHRM3 P20309 2/20 0.38
MAPK1 P28482 1/20 0.38
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7106510 0.88 KMT2A (0.47) KMT2ACYP2D6SRCMEN1TSHR
SCHEMBL9051580 0.82 KMT2A (0.45) KMT2ACYP2D6SRCMEN1TSHR
SCHEMBL4642047 0.81 KMT2A (0.46) KMT2ACYP2D6SRCMEN1TSHR
SCHEMBL4644768 0.80 CYP2D6 (0.39) KMT2ACYP2D6SRCMEN1TSHR
SCHEMBL15514394 0.80 KMT2A (0.44) KMT2ACYP2D6SRCMEN1TSHR
SCHEMBL4647843 0.80 L3MBTL1 (0.52) KMT2ACYP2D6MEN1TSHRCYP1A2
SCHEMBL29819688 0.78 CHRM1 (0.49) KMT2ACYP2D6SRCTSHRCYP1A2
SCHEMBL11600732 0.76 KMT2A (0.44) KMT2ACYP2D6SRCMEN1TSHR
SCHEMBL1526022 0.76 KMT2A (0.64) KMT2AMEN1TSHRLMNACHRM2
SCHEMBL4645788 0.75 PRSS1 (0.38) KMT2ACYP2D6MEN1CYP1A2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed