Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9051580 | 0.89 | KMT2A (0.45) | KMT2ACYP2D6SRCTSHRLMNA | |
| SCHEMBL4642041 | 0.88 | KMT2A (0.41) | KMT2ACYP2D6SRCTSHRLMNA | |
| SCHEMBL4642047 | 0.88 | KMT2A (0.46) | KMT2ACYP2D6SRCTSHRLMNA | |
| SCHEMBL29819688 | 0.84 | CHRM1 (0.49) | KMT2ACYP2D6SRCTSHRLMNA | |
| SCHEMBL4644768 | 0.83 | CYP2D6 (0.39) | KMT2ACYP2D6SRCTSHRLMNA | |
| SCHEMBL11600732 | 0.83 | KMT2A (0.44) | KMT2ACYP2D6SRCTSHRLMNA | |
| SCHEMBL1526022 | 0.83 | KMT2A (0.64) | KMT2ATSHRLMNAMEN1CHRM2 | |
| SCHEMBL15514394 | 0.83 | KMT2A (0.44) | KMT2ACYP2D6SRCTSHRLMNA | |
| SCHEMBL16904038 | 0.81 | CYP2D6 (0.43) | KMT2ACYP2D6SRCTSHRLMNA | |
| SCHEMBL8675334 | 0.81 | L3MBTL1 (0.56) | KMT2ACYP2D6SRCTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792936-B1 | Process for the preparation of optically active 2-halo-1-(substituted phenyl) ethanol | MITSUBISHI CHEM CORP (JP) | 2003-01-29 | — | — | EP | disclosed |
| US-5841001-A | ALLOWING 2-HALO-1-(SUBSTITUTED PHENYL)ETHANOL TO CONTACT ENZYME STEREOSELECTIVELY CATALYZING ESTER INTERCHANGE IN PRESENCE OF CARBOXYLIC ANHYDRIDE | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0792936-A2 | Process for the preparation of optically active 2-halo-1-(substituted phenyl) ethanol | Mitsubishi Chemical Corporation (JP) | 1997-09-03 | — | — | EP | disclosed |
| US-4110465-A | ANTIINFLAMMATORY, ANTITHROMBOSIS | ELI LILLY AND COMPANY (US) | 1978-08-29 | — | — | US | disclosed |