Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4643655 | 0.91 | TOP1 (0.45) | ALDH1A1TOP1TRPV1TDP1KMT2A | |
| SCHEMBL4642129 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TOP1TDP1KMT2ATSHR | |
| SCHEMBL466545 | 0.78 | TDP1 (0.63) | ALDH1A1TRPV1TDP1KMT2AKDM4E | |
| SCHEMBL8594687 | 0.77 | TOP1 (0.58) | ALDH1A1TOP1MAOBKEAP1MAPK1 | |
| SCHEMBL6279310 | 0.76 | TDP1 (0.61) | ALDH1A1TRPV1TDP1KMT2AKDM4E | |
| SCHEMBL27384314 | 0.75 | MAOB (0.50) | ALDH1A1TOP1TDP1KMT2ATSHR | |
| SCHEMBL28092341 | 0.75 | HDAC1 (0.58) | ALDH1A1TDP1KMT2AKEAP1MAPK1 | |
| SCHEMBL3154424 | 0.74 | PAM (0.47) | ALDH1A1TDP1AKT1LMNAMAOB | |
| SCHEMBL8861535 | 0.73 | NPC1 (0.47) | ALDH1A1TOP1KMT2AMAOBKEAP1 | |
| SCHEMBL248114 | 0.73 | TSHR (0.58) | ALDH1A1KMT2ATSHRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487928-B1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2008-08-13 | — | — | EP | disclosed |
| EP-1487928-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | Jotun AS (NO) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080747-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2003-10-02 | — | — | WO | disclosed |