SCHEMBL4642332

SCHEMBL4642332

Cc1ccc([Si](OC(=O)CCCCO)(c2ccc(C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 2/20 0.36
TDP1 Q9NUW8 3/20 0.35
HDAC1 Q13547 3/20 0.34
HDAC2 Q92769 3/20 0.34
HDAC3 O15379 2/20 0.34
HDAC10 Q969S8 2/20 0.34
HDAC11 Q96DB2 2/20 0.34
HDAC8 Q9BY41 2/20 0.34
HDAC6 Q9UBN7 2/20 0.34
HDAC4 P56524 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC9 Q9UKV0 1/20 0.34
HDAC5 Q9UQL6 1/20 0.34
CYP4F2 P78329 2/20 0.34
CYP4A11 Q02928 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
NCOR2 Q9Y618 1/20 0.33
KMT2A Q03164 3/20 0.33
ALDH1A1 P00352 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642082 0.95 L3MBTL1 (0.34) FBP1TDP1HDAC1HDAC2HDAC3
SCHEMBL4644558 0.88 L3MBTL1 (0.36) TDP1CYP4F2CYP4A11L3MBTL1KMT2A
SCHEMBL4643870 0.86 L3MBTL1 (0.36) TDP1HDAC1HDAC2HDAC3HDAC10
SCHEMBL4644326 0.84 L3MBTL1 (0.37) TDP1L3MBTL1KMT2AALDH1A1CYP2C19
SCHEMBL4645869 0.84 KMT2A (0.35) TDP1HDAC1HDAC2HDAC3HDAC10
SCHEMBL4644427 0.83 GPR84 (0.36) TDP1HDAC1HDAC2HDAC3HDAC10
SCHEMBL4643859 0.81 CYP2C19 (0.36) TDP1L3MBTL1KMT2AALDH1A1RAB9A
SCHEMBL4642549 0.80 L3MBTL1 (0.35) TDP1L3MBTL1KMT2AALDH1A1CYP2C19
SCHEMBL4645473 0.80 L3MBTL1 (0.35) TDP1L3MBTL1KMT2AALDH1A1CYP2C19
SCHEMBL4642474 0.78 MAPT (0.38) TDP1HDAC1HDAC2HDAC3HDAC10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed