Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.45 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640475 | 0.98 | FOLH1 (0.56) | FOLH1MRGPRX4NR1H4NR4A2KIF11 | |
| SCHEMBL4642854 | 0.98 | FOLH1 (0.56) | FOLH1MRGPRX4NR1H4NR4A2KIF11 | |
| SCHEMBL10950038 | 0.83 | FOLH1 (0.54) | FOLH1MRGPRX4NR1H4NR4A2KIF11 | |
| SCHEMBL4642851 | 0.82 | CA2 (0.41) | FOLH1MRGPRX4 | |
| SCHEMBL4640477 | 0.80 | LOXL2 (0.60) | FOLH1MRGPRX4HIF1AKMT2A | |
| SCHEMBL4641021 | 0.79 | TDP1 (0.59) | FOLH1CYP2C9HIF1AKMT2A | |
| SCHEMBL9698969 | 0.79 | FOLH1 (0.61) | FOLH1MRGPRX4NR4A2CYP2D6CYP2C9 | |
| SCHEMBL31506361 | 0.77 | FOLH1 (0.59) | FOLH1MRGPRX4NR1H4CYP2D6CYP2C9 | |
| SCHEMBL849483 | 0.77 | FOLH1 (0.59) | FOLH1MRGPRX4NR4A2CYP2D6CYP2C9 | |
| SCHEMBL1690483 | 0.77 | FOLH1 (0.59) | FOLH1MRGPRX4NR1H4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120391-B1 | MOLECULAR COMPOUNDS CONTAINING NOVEL CARBOXYLIC ACID DERIVATIVES AS THE CONSTITUENT COMPOUND | NIPPON SODA CO (JP) | 2008-08-06 | — | — | EP | disclosed |
| US-6566548-B1 | Alkylene- or phenylene- tetrabenzoic acids and derivatives | NIPPON SODA CO., LTD. (JP) | 2003-05-20 | — | — | US | disclosed |
| EP-1120391-A1 | MOLECULAR COMPOUNDS CONTAINING NOVEL CARBOXYLIC ACID DERIVATIVES AS THE CONSTITUENT COMPOUND | NIPPON SODA CO., LTD. (JP) | 2001-08-01 | — | — | EP | disclosed |