SCHEMBL4643084

SCHEMBL4643084

CCCC(C)(C)OC(=O)c1cc(Br)c(C)cc1C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.36
TSHR P16473 1/20 0.36
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4641162 1.00 HSD17B10 (0.36) HSD17B10TSHRLCKFYN
SCHEMBL4641161 0.94 TSHR (0.32) HSD17B10TSHR
SCHEMBL4643912 0.92 HSD17B10 (0.40) HSD17B10TSHRLCKFYN
SCHEMBL4644128 0.90 HSD17B10 (0.33) HSD17B10TSHR
SCHEMBL4639957 0.86 HSD17B10 (0.36) HSD17B10TSHRLCKFYN
SCHEMBL4639980 0.86 HSD17B10 (0.36) HSD17B10TSHRLCKFYN
SCHEMBL4643908 0.85 ESR1 (0.34) HSD17B10TSHR
SCHEMBL4640890 0.85 HSD17B10 (0.35) HSD17B10TSHRLCKFYN
SCHEMBL4640941 0.85 ESR1 (0.32) HSD17B10
SCHEMBL4641233 0.85 ESR1 (0.32) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1188739-B1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO LTD (JP) 2008-08-13 EP disclosed
US-6670497-B2 Dialkyl (at least one of which is a C4-8 tertiary alkyl) ester of an alkyl- or halo-substituted phthalic acid; used in an olefin polymerization catalyst TOHO TITANIUM CO., LTD. (JP) 2003-12-30 US disclosed
US-20030036594-A1 Phthalic diester derivatives and electron donors TOHO TITANIUM CO., LTD. (JP) 2003-02-20 US disclosed
EP-1188739-A1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO., LTD. (JP) 2002-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030036594-A1 Phthalic diester derivatives and electron donors HPD, ETFA, PPOX HSD17B10 117/4885TSHR 4817/4885LCK 2375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.