SCHEMBL4643204

SCHEMBL4643204

[CH2]C(=O)Oc1c(Cl)cc(Br)cc1Br

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.40
POLB P06746 1/20 0.38
KDM4E B2RXH2 4/20 0.35
ALOX15 P16050 3/20 0.35
TPMT P51580 2/20 0.35
TSHR P16473 2/20 0.34
APOBEC3A P31941 1/20 0.34
HTT P42858 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
CYP1A2 P05177 3/20 0.33
MEN1 O00255 2/20 0.33
CYP2C19 P33261 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
NMT1 P30419 1/20 0.33
MAPT P10636 1/20 0.33
AKR1C4 P17516 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4641535 0.90 POLB (0.40) HSD17B10POLBKDM4ETSHRHTT
SCHEMBL4644330 0.86 HSD17B10 (0.46) HSD17B10ALOX15TPMTTSHRAPOBEC3A
SCHEMBL4643215 0.81 HSD17B10 (0.43) HSD17B10POLBKDM4EALOX15TPMT
SCHEMBL4643495 0.81 HSD17B10 (0.37) HSD17B10POLBKDM4EALOX15TPMT
SCHEMBL4644473 0.79 HSD17B10 (0.38) HSD17B10POLBKDM4EALOX15TPMT
SCHEMBL4641402 0.79 HSD17B10 (0.38) HSD17B10POLBKDM4EALOX15TPMT
SCHEMBL4642291 0.78 HSD17B10 (0.35) HSD17B10POLBKDM4EALOX15TPMT
SCHEMBL4643493 0.77 HSD17B10 (0.40) HSD17B10POLBKDM4EALOX15TPMT
SCHEMBL4644450 0.76 HSD17B10 (0.36) HSD17B10POLBKDM4EALOX15TPMT
SCHEMBL4646986 0.76 VCAM1 (0.36) HSD17B10POLBKDM4EALOX15TPMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed