Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL4643549

O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.c1ccc([S+](c2ccccc2)c2ccc(Oc3ccc([I+]c4ccc(Oc5ccc([S+](c6ccccc6)c6ccccc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.37
GPR3 P46089 1/20 0.36
PTPN1 P18031 1/20 0.36
LMNA P02545 3/20 0.35
HTT P42858 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
PGR P06401 3/20 0.34
NR3C1 P04150 2/20 0.34
AR P10275 1/20 0.34
ESR2 Q92731 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
MMP1 P03956 3/20 0.33
MMP8 P22894 3/20 0.33
FFAR1 O14842 2/20 0.33
MMP3 P08254 2/20 0.33
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33
MMP14 P50281 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL6022880 0.99 SOS1 (0.36) SOS1GPR3PTPN1LMNAHTT
Trifluoromethanesulfonic Acid SCHEMBL5427818 0.91 SOS1 (0.43) SOS1GPR3PTPN1LMNAHTT
Trifluoromethanesulfonic Acid SCHEMBL51417 0.90 SOS1 (0.46) SOS1GPR3PTPN1LMNAHTT
Trifluoromethanesulfonic Acid SCHEMBL4644148 0.88 HTT (0.35) SOS1GPR3PTPN1LMNAHTT
Trifluoromethanesulfonic Acid SCHEMBL4643748 0.88 HTT (0.40) GPR3PTPN1HTTSMN1; SMN2NR3C1
SCHEMBL4643827 0.87 SOS1 (0.33) SOS1LMNAHTTSMN1; SMN2PGR
Trifluoromethanesulfonic Acid SCHEMBL4643720 0.87 GPR3 (0.38) GPR3PTPN1CA1CA2CA9
SCHEMBL4643684 0.86 SOS1 (0.32) SOS1LMNAHTTSMN1; SMN2PGR
Trifluoromethanesulfonic Acid SCHEMBL4645187 0.85 HTT (0.35) SOS1GPR3PTPN1LMNAHTT
Trifluoromethanesulfonic Acid SCHEMBL4643751 0.85 HTT (0.33) SOS1GPR3PTPN1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1443042-B1 HYBRID ONIUM SALT WAKO PURE CHEM IND LTD (JP) 2008-08-13 EP disclosed
US-7101918-B2 Hybrid type onium salt WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2006-09-05 US disclosed
US-20050020710-A1 Hybrid onium salt WAKO PURE CHEMICALS INDUSTRIES, LTD. (JP) 2005-01-27 US disclosed
EP-1443042-A1 HYBRID ONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2004-08-04 EP disclosed