SCHEMBL4643680

SCHEMBL4643680

COc1ccc(CC(=O)C(=O)CCCCO)cc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.47
CTBP2 P56545 1/20 0.46
F2RL1 P55085 1/20 0.46
ALOX5 P09917 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
POLB P06746 2/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C19 P33261 1/20 0.44
USP2 O75604 1/20 0.44
TP53 P04637 1/20 0.44
KDM4E B2RXH2 1/20 0.44
PLAAT3 P53816 1/20 0.44
PLAAT5 Q96KN8 1/20 0.44
PLAAT2 Q9NWW9 1/20 0.44
PLAAT4 Q9UL19 1/20 0.44
LDHA P00338 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642078 0.95 HTT (0.53) HTTSMN1; SMN2CTBP2F2RL1ALOX5
SCHEMBL4641568 0.88 HTT (0.56) HTTSMN1; SMN2CTBP2F2RL1POLB
SCHEMBL4641839 0.86 HTT (0.50) HTTSMN1; SMN2CTBP2F2RL1ALOX5
SCHEMBL10708818 0.85 ALOX5 (0.62) HTTF2RL1ALOX5POLBALDH1A1
SCHEMBL4641825 0.84 HTT (0.51) HTTSMN1; SMN2CTBP2F2RL1ALOX5
SCHEMBL28754868 0.83 HTT (0.50) HTTSMN1; SMN2CTBP2F2RL1ALOX5
SCHEMBL4643470 0.81 HTT (0.59) HTTSMN1; SMN2CTBP2F2RL1POLB
SCHEMBL4644014 0.80 KDM4E (0.51) HTTSMN1; SMN2POLBALDH1A1KDM4E
SCHEMBL4642217 0.80 HTT (0.54) HTTSMN1; SMN2CTBP2F2RL1POLB
SCHEMBL4642061 0.78 L3MBTL1 (0.45) CTBP2L3MBTL1POLBALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100519671-C Film-forming polymer and antifouling paint JOTUN AS (NO) 2009-07-29 CN disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
CN-1643085-A Film-forming polymer and antifouling paint JOTUN AS (NO) 2005-07-20 CN disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed