SCHEMBL4643797

SCHEMBL4643797

CCCCC(O)C(=O)O[SiH](C)C

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 3/20 0.44
FFAR1 O14842 1/20 0.44
CA2 P00918 3/20 0.41
CA1 P00915 2/20 0.41
TSHR P16473 2/20 0.37
CYP3A4 P08684 1/20 0.37
ATM Q13315 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAPK1 P28482 1/20 0.36
NAAA Q02083 1/20 0.35
ZDHHC7 Q9NXF8 1/20 0.35
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4646606 0.79 TSHR (0.36) TSHRALDH1A1
SCHEMBL6663357 0.79 GPR84 (0.50) GPR84FFAR1CA2CA1TSHR
SCHEMBL4645293 0.78 CA2 (0.40) CA2CA1TSHRCYP3A4ATM
SCHEMBL27724226 0.77 GPR84 (0.48) GPR84FFAR1CA2CA1TSHR
SCHEMBL309000 0.77 GPR84 (0.48) GPR84FFAR1CA2CA1TSHR
SCHEMBL438579 0.77 GPR84 (0.48) GPR84FFAR1CA2CA1TSHR
SCHEMBL149523 0.77 CA2 (0.61) GPR84FFAR1CA2CA1TSHR
SCHEMBL7947554 0.77 CA2 (0.61) GPR84FFAR1CA2CA1TSHR
SCHEMBL4717732 0.75 GPR84 (0.47) GPR84FFAR1CA2CA1TSHR
Water SCHEMBL28120707 0.75 CA2 (0.59) GPR84FFAR1CA2CA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed