SCHEMBL4644155

SCHEMBL4644155

ICc1c2ccccc2c(CI)c2ccccc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
HSD17B10 Q99714 4/20 0.36
HPGD P15428 2/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
CASP1 P29466 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TNNI3 P19429 1/20 0.36
TNNT2 P45379 1/20 0.36
TNNC1 P63316 1/20 0.36
CYP2A6 P11509 2/20 0.35
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HTR2A P28223 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CYP1A2 P05177 4/20 0.33
CYP2C19 P33261 2/20 0.33
IDO1 P14902 1/20 0.33
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11621313 0.87 CYP3A4 (0.46) ALDH1A1HSD17B10HPGDCASP1MEN1
SCHEMBL11666112 0.81 PDE4B (0.37) ALDH1A1MEN1KMT2AKDM4EGAA
SCHEMBL14499087 0.79 KDM4E (0.57) ALDH1A1HSD17B10HPGDCASP1KMT2A
Triphenylene SCHEMBL31563605 0.69 HPRT1 (0.53) ALDH1A1HSD17B10HPGDALOX12CYP2A6
SCHEMBL5488099 0.68 ALDH1A1 (0.39) ALDH1A1HSD17B10HPGDALOX15ALOX12
SCHEMBL14627440 0.67 GPR3 (0.39) ALDH1A1HSD17B10HPGDALOX15ALOX12
SCHEMBL332253 0.67 IDO1 (0.45) ALDH1A1HSD17B10HPGDMEN1KMT2A
SCHEMBL2317562 0.67 TP53 (0.45) ALDH1A1HSD17B10HPGDMEN1KMT2A
SCHEMBL1719724 0.67 ALDH1A1 (0.45) ALDH1A1HSD17B10MEN1KMT2ATNNI3
SCHEMBL31613081 0.67 HTR2A (0.67) ALDH1A1HSD17B10MEN1KMT2ATNNI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4091578-B1 METHOD FOR PRODUCING PLATE DENTURE TOKUYAMA DENTAL CORP (JP) 2024-10-09 EP disclosed
US-11857385-B2 Method of producing plate denture, curable composition for stereolithography, and plate denture production kit TOKUYAMA DENTAL CORPORATION (JP) 2024-01-02 US disclosed
CN-114929158-B Method for producing denture, curable composition for photoforming, and kit for producing denture 株式会社德山齿科 2023-10-20 CN disclosed
US-20230137898-A1 METHOD OF PRODUCING PLATE DENTURE, CURABLE COMPOSITION FOR STEREOLITHOGRAPHY, AND PLATE DENTURE PRODUCTION KIT TOKUYAMA DENTAL CORPORATION (JP) 2023-05-04 US disclosed
EP-4091578-A1 METHOD FOR PRODUCING PLATE DENTURE, CURABLE STEREOLITHOGRAPHIC COMPOSITION, AND PLATE DENTURE PRODUCTION KIT Tokuyama Dental Corporation (JP) 2022-11-23 EP disclosed
CN-114929158-A Method for producing a denture, curable composition for photo-molding, and kit for producing a denture 株式会社德山齿科 2022-08-19 CN disclosed
US-10991517-B2 Molecular photon upconversion using organic-inorganic hybrid interfaces The Florida State University Research Foundation, Inc. (US) 2021-04-27 US disclosed
US-20170236653-A1 MOLECULAR PHOTON UPCONVERSION USING ORGANIC-INORGANIC HYBRID INTERFACES The Florida State University Research Foundation, Inc. 2017-08-17 US disclosed
CN-103988313-A Method for manufacturing silicon substrate having textured structure TOKUYAMA CORPROATION 2014-08-13 CN disclosed
EP-1591098-B1 Cationically curable composition for dental use TOKUYAMA CORP (JP) 2008-08-13 EP disclosed
EP-1431315-B1 Photopolymerization initiator and photopolymerizable composition TOKUYAMA CORP (JP) 2007-10-17 EP disclosed
US-7030171-B2 Process for producing vinyl polymer having functional group at end and vinyl polymer having functional group at end SEKISUI CHEMICAL CO., LTD. (JP) 2006-04-18 US disclosed
CN-1732883-A Cationically curable composition for dental use TOKUYAMA CORP (JP) 2006-02-15 CN disclosed
US-20050250868-A1 Cationically curable composition for dental use TOKUYAMA CORPORATION (JP) 2005-11-10 US disclosed
EP-1591098-A1 Cationically curable composition for dental use TOKUYAMA CORPORATION (JP) 2005-11-02 EP disclosed
US-20040186195-A1 Photopolymerization initiator and photopolymerizable composition TOKUYAMA CORPORATION (JP) 2004-09-23 US disclosed
EP-1431315-A2 Photopolymerization initiator and photopolymerizable composition Tokuyama Corporation (JP) 2004-06-23 EP disclosed
US-20040092619-A1 Process for producing vinyl polymer having functional group at end and vinyl polymer having functional group at end WAKIYA TAKESHI (JP) 2004-05-13 US disclosed
US-6693142-B1 POLYMERIZATION REACTION OF VINYL MONOMERS IN PRESENCE OF HALOGEN COMPOUND AND SUBSTITUTING WITH SUCH AS HYDROXYL, AMINO, VINYL OR SILYL GROUPS SEKISUI CHEMICAL CO., LTD. (JP) 2004-02-17 US disclosed
EP-1243599-A1 PROCESS FOR PRODUCING VINYL POLYMER HAVING FUNCTIONAL GROUP AT END AND VINYL POLYMER HAVING FUNCTIONAL GROUP AT END SEKISUI CHEMICAL CO., LTD. (JP) 2002-09-25 EP disclosed