SCHEMBL4644201

SCHEMBL4644201

c1ccc([I+]c2ccc(Oc3ccc([S+](c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 7/20 0.41
TSHR P16473 1/20 0.41
NR1H2 P55055 1/20 0.38
BAX Q07812 1/20 0.38
MAOA P21397 1/20 0.38
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
KDM1A O60341 1/20 0.34
GSTP1 P09211 1/20 0.32
SOS1 Q07889 1/20 0.32
CA9 Q16790 1/20 0.32
PARP10 Q53GL7 1/20 0.32
PLA2G2A P14555 1/20 0.32
SRD5A2 P31213 2/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
NLRP3 Q96P20 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4643982 0.98 LTA4H (0.42) LTA4HTSHRNR1H2BAXMAOA
Perchlorate SCHEMBL4643122 0.93 LTA4H (0.35) LTA4HTSHRNR1H2BAXMAOA
Perchlorate SCHEMBL4643309 0.91 LTA4H (0.37) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL6658051 0.90 HTT (0.44) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL6660652 0.90 HTT (0.44) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL686239 0.85 LTA4H (0.55) LTA4HTSHRNR1H2BAXMAOA
Trifluoromethanesulfonic Acid SCHEMBL6022880 0.84 SOS1 (0.36) CA1CA2SOS1CA9KMT2A
SCHEMBL686232 0.83 LTA4H (0.60) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL2993064 0.83 LTA4H (0.60) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL3455003 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1443042-B1 HYBRID ONIUM SALT WAKO PURE CHEM IND LTD (JP) 2008-08-13 EP disclosed