Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 7/20 | 0.46 |
| ▸ | CA1 | P00915 | 7/20 | 0.46 |
| ▸ | CA2 | P00918 | 7/20 | 0.46 |
| ▸ | CA9 | Q16790 | 7/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2279724 | 0.92 | TDP1 (0.53) | TDP1IDO1CA12CA1CA2 | |
| SCHEMBL20500827 | 0.85 | TDP1 (0.50) | TDP1IDO1CA12CA1CA2 | |
| SCHEMBL28500736 | 0.82 | TDP1 (0.47) | TDP1IDO1CA12CA1CA2 | |
| SCHEMBL1063374 | 0.81 | CA12 (0.60) | TDP1IDO1CA12CA1CA2 | |
| SCHEMBL222081 | 0.81 | TDP1 (0.50) | TDP1IDO1CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL27999755 | 0.81 | TDP1 (0.46) | TDP1IDO1CA12CA1CA2 | |
| SCHEMBL23728804 | 0.80 | TDP1 (0.49) | TDP1IDO1CA12CA1CA2 | |
| SCHEMBL22515370 | 0.80 | TDP1 (0.49) | TDP1IDO1CA12CA1CA2 | |
| SCHEMBL21113607 | 0.80 | TDP1 (0.49) | TDP1IDO1CA12CA1CA2 | |
| SCHEMBL22939675 | 0.80 | TDP1 (0.49) | TDP1IDO1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685102-A4 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD (KR) | 2008-08-20 | — | — | EP | disclosed |
| EP-1685102-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG Life Sciences Ltd. (KR) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005047251-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2005-05-26 | — | — | WO | disclosed |