SCHEMBL222081

SCHEMBL222081

CC(C)(C)OC(=O)NCCOCCN

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.50
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
GAA P10253 1/20 0.47
CA12 O43570 7/20 0.47
CA1 P00915 7/20 0.47
CA2 P00918 7/20 0.47
CA9 Q16790 7/20 0.47
IDO1 P14902 1/20 0.43
EPHX1 P07099 1/20 0.42
BCHE P06276 1/20 0.39
CNR2 P34972 1/20 0.39
ADRB2 P07550 1/20 0.38
HTR1A P08908 1/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9331881 0.98 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL22939675 0.98 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL2805155 0.98 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL13788602 0.98 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL450913 0.98 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL23728804 0.98 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL35060 0.98 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL21113607 0.98 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL22515370 0.98 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL30945310 0.98 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 713 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119564946-A Azo calixarene-based broad-spectrum quantitative medicine-carrying acupuncture needle, and preparation method and application thereof 天津中医药大学第一附属医院 2025-03-07 CN claimed
CN-119241380-A Preparation method and application of clay mineral surface hydration inhibitor 西南石油大学 2025-01-03 CN claimed
CN-118955953-A Super-strain self-adhesive flexible hydrogel and preparation method and application thereof 广东工业大学 2024-11-15 CN claimed
CN-116574081-B Chlorogenic acid-Huang Qinsu conjugate and preparation method and application thereof 江西省科学院应用化学研究所 2023-09-05 CN claimed
CN-116574081-A Chlorogenic acid-Huang Qinsu conjugate and preparation method and application thereof 江西省科学院应用化学研究所 2023-08-11 CN claimed
US-20230118911-A1 PROTEOLYSIS TARGETING CHIMERA (PROTAC) FOR DEGRADATION OF AURORA A-KINASE JULIUS-MAXIMILIANS-UNIVERSITAET WUERZBURG (DE) 2023-04-20 US claimed
CN-109456250-B Thermal Activation Delayed Fluorescence (TADF) nano probe, preparation method thereof and application thereof in biological imaging 哈尔滨医科大学 2022-03-04 CN claimed
CN-109456250-A Hot activation delayed fluorescence (TADF) nano-probe and preparation method thereof and the application in bio-imaging 哈尔滨医科大学 2019-03-12 CN claimed
CN-122036705-A PROTAC compound of targeted PI3K alpha and preparation and application thereof 三亚深海化合物资源中心 2026-05-15 CN disclosed
CN-122036541-A Amino acid-based ionizable lipid compound, and preparation method and application thereof 中国科学院广州生物医药与健康研究院 2026-05-15 CN disclosed
EP-4736882-A2 TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE Cullgen (Shanghai), Inc. (CN) 2026-05-06 EP disclosed
US-12617905-B2 Crosslinked alginic acid MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2026-05-05 US disclosed
EP-4731611-A1 TARGETED DEGRADERS OF HIV-1 NEF FOR THE TREATMENT OF HIV DISEASE UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2026-04-29 EP disclosed
US-20260108618-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2026-04-23 US disclosed
US-6114321-A Porphyrin derivatives, pharmaceutical agents that contain the latter, and their use in photodynamic therapy and MRI diagnosis SCHERING AKTIENGESELLSCHAFT (DE) 2000-09-05 US disclosed
US-5773612-A VASOPRESSIN OR OXYTOCIN RECEPTORS SANOFI (FR) 1998-06-30 US disclosed
US-5594023-A 1,3-dihydroindol-2-one derivatives substituted in the 3-position by a nitrogen-containing group, their preparation and the pharmaceutical compositions in which they are present SANOFI (FR) 1997-01-14 US disclosed
EP-0687251-A1 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS SANOFI (FR) 1995-12-20 EP disclosed
WO-1995018105-A1 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS SANOFI (FR) 1995-07-06 WO disclosed
US-5053503-A For joining antibodies and metallic radionuclides CENTOCOR (US) 1991-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230118911-A1 PROTEOLYSIS TARGETING CHIMERA (PROTAC) FOR DEGRADATION OF AURORA A-KINASE CRBN, AURKC, AURKB TDP1 3529/4885MAOA 4610/4885MAOB 3875/4885
US-12617905-B2 Crosslinked alginic acid ALG1, ANXA6, HEXB TDP1 1973/4885MAOA 726/4885MAOB 422/4885
US-20260108618-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, FCGR1A, FCGR2A TDP1 3694/4885MAOA 1115/4885MAOB 1349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.