SCHEMBL22939675

SCHEMBL22939675

CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCN

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.49
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
GAA P10253 1/20 0.46
CA12 O43570 7/20 0.46
CA1 P00915 7/20 0.46
CA2 P00918 7/20 0.46
CA9 Q16790 7/20 0.46
IDO1 P14902 1/20 0.42
EPHX1 P07099 1/20 0.41
BCHE P06276 1/20 0.41
CNR2 P34972 1/20 0.41
ADRB2 P07550 1/20 0.40
HTR1A P08908 1/20 0.40
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30945310 1.00 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL35060 1.00 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL9331881 1.00 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL13788602 1.00 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL2805155 1.00 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL450913 1.00 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL23728804 1.00 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL21113607 1.00 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL22515370 1.00 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL30062304 1.00 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137822-A1 MULTIVALENT IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY ABDERA THERAPEUTICS INC (US) 2026-05-21 US disclosed
US-12624038-B2 Molecules and methods related to treatment of uncontrolled cellular proliferation ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) 2026-05-12 US disclosed
EP-4676538-A2 BI-SPECIFIC ADAPTERS AND THEIR USE WITH UNIVERSAL CAR-T CELLS IN THE TREATMENT OF CAIX-EXPRESSING TUMORS Purdue Research Foundation (US) 2026-01-14 EP disclosed
US-20250282876-A1 STABLE Fc FRAGMENTS, CONJUGATES, COMPOSITIONS, AND METHODS OF USE PURDUE RESEARCH FOUNDATION 2025-09-11 US disclosed
US-20250255956-A1 DUAL AND TRIPLE HAPTEN CONJUGATES, COMPOSITIONS, PROCESSES FOR MAKING, AND METHODS OF TREATMENT THEREWITH PURDUE RESEARCH FOUNDATION 2025-08-14 US disclosed
EP-4598928-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-08-13 EP disclosed
EP-4577578-A1 DLL3 BINDING MOLECULES AND USES THEREOF Abdera Therapeutics Inc. (US) 2025-07-02 EP disclosed
EP-4577250-A1 MULTIVALENT IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY Abdera Therapeutics Inc. (US) 2025-07-02 EP disclosed
US-12344675-B2 Polypeptide comprising a single-domain antibody variable region that binds delta-like ligand 3 (DLL3) and method of use thereof to make a radionuclide complex Abdera Therapeutics Inc. (US) 2025-07-01 US disclosed
WO-2025085647-A2 FC FRAGMENTS, CONJUGATES, COMPOSITIONS, AND METHODS OF USE KAMRA MOHINI (US) 2025-04-24 WO disclosed
EP-4221756-A1 COMPOUNDS AND THEIR USE IN TREATING CANCER Astrazeneca AB (SE) 2023-08-09 EP disclosed
CN-116472292-A Modified proteins and protein degrading agents 上海睿跃生物科技有限公司 2023-07-21 CN disclosed
WO-2023078813-A1 HETEROBIFUNCTIONAL MOLECULES AS TEAD INHIBITORS MERCK PATENT GMBH (DE) 2023-05-11 WO disclosed
WO-2023080652-A1 ANDROGEN RECEPTOR DEGRADERS FOR THE TREATMENT OF CASTRATION-RESISTANT PROSTATE CANCER AND USE THEREOF AUTOTAC INC. (KR) 2023-05-11 WO disclosed
US-20230057177-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2023-02-23 US disclosed
WO-2022175750-A1 IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY Abdera Therapeutics Inc. (CA) 2022-08-25 WO disclosed
US-20220251097-A1 MOLECULES AND METHODS RELATED TO TREATMENT OF UNCONTROLLED CELLULAR PROLIFERATION ST. JUDE CHILDREN'S RESEARCH HOSPITAL 2022-08-11 US disclosed
WO-2022138550-A1 REAGENT FOR BLOOD VESSEL IMAGING 国立大学法人群馬大学 2022-06-30 WO disclosed
WO-2022069520-A1 COMPOUNDS AND THEIR USE IN TREATING CANCER ASTRAZENECA AB (SE) 2022-04-07 WO disclosed
WO-2021022076-A1 MOLECULES AND METHODS RELATED TO TREATMENT OF UNCONTROLLED CELLULAR PROLIFERATION ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) 2021-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250255956-A1 DUAL AND TRIPLE HAPTEN CONJUGATES, COMPOSITIONS, PROCESSES FOR MAKING, AND METHODS OF TREATMENT THEREWITH HAVCR2, CD4, CD44 TDP1 2404/4885MAOA 3926/4885MAOB 3627/4885
US-20220251097-A1 MOLECULES AND METHODS RELATED TO TREATMENT OF UNCONTROLLED CELLULAR PROLIFERATION MKI67, BCL2, PCNA TDP1 2146/4885MAOA 2464/4885MAOB 1943/4885
US-12344675-B2 Polypeptide comprising a single-domain antibody variable region that binds delta-like ligand 3 (DLL3) and method of use thereof to make a radionuclide complex DLK1, CD2BP2, IGLV6-57 TDP1 3937/4885MAOA 4868/4885MAOB 4866/4885
US-20250282876-A1 STABLE Fc FRAGMENTS, CONJUGATES, COMPOSITIONS, AND METHODS OF USE FCGR3B, FCGR2A, FCGR1A TDP1 3810/4885MAOA 3094/4885MAOB 3078/4885
US-20260137822-A1 MULTIVALENT IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY FCGR2A, FCGR3B, FCGR1A TDP1 3013/4885MAOA 3937/4885MAOB 3900/4885
US-12624038-B2 Molecules and methods related to treatment of uncontrolled cellular proliferation CCNC, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MKI67 TDP1 2948/4885MAOA 2273/4885MAOB 1827/4885
US-20230057177-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS DDB1, DCLRE1A, MDM2 TDP1 136/4885MAOA 3799/4885MAOB 3105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.