SCHEMBL4644429

SCHEMBL4644429

[CH2]CCCC(=O)Oc1ccc(C(C)=O)cc1C=O

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.39
CREBBP Q92793 1/20 0.37
ALDH1A1 P00352 5/20 0.36
HIF1A Q16665 1/20 0.36
MEN1 O00255 2/20 0.35
ALOX15 P16050 1/20 0.35
KDM4E B2RXH2 2/20 0.35
POLB P06746 1/20 0.35
HPGD P15428 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MAPT P10636 1/20 0.34
TOP2A P11388 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644730 0.92 CREBBP (0.38) KMT2ACREBBPALDH1A1HIF1AMEN1
SCHEMBL4641836 0.86 CREBBP (0.40) KMT2ACREBBPALDH1A1HIF1AMEN1
SCHEMBL4644037 0.82 KDM4E (0.49) KMT2AALDH1A1MEN1KDM4ETDP1
SCHEMBL4644462 0.81 PTGDR2 (0.52) KMT2AALDH1A1MEN1ALOX15KDM4E
SCHEMBL4642017 0.79 PTGDR2 (0.49) KMT2AALDH1A1MEN1KDM4EHPGD
SCHEMBL4641633 0.79 CREBBP (0.40) KMT2ACREBBPALDH1A1HIF1AMEN1
SCHEMBL4641637 0.78 TSHR (0.50) KMT2ACREBBPALDH1A1MEN1KDM4E
SCHEMBL4645139 0.76 KMT2A (0.43) KMT2AKDM4EPOLB
SCHEMBL2178669 0.75 ALOX15 (0.48) ALOX15TOP2A
SCHEMBL2177812 0.75 ALOX15 (0.48) ALOX15TOP2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed