SCHEMBL4644730

SCHEMBL4644730

[CH2]CCC(=O)Oc1ccc(C(C)=O)cc1C=O

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CREBBP Q92793 1/20 0.38
ALDH1A1 P00352 6/20 0.38
HIF1A Q16665 1/20 0.38
KMT2A Q03164 6/20 0.37
MEN1 O00255 3/20 0.37
KDM4E B2RXH2 2/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 2/20 0.35
HPGD P15428 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644429 0.92 KMT2A (0.39) CREBBPALDH1A1HIF1AKMT2AMEN1
SCHEMBL4641836 0.89 CREBBP (0.40) CREBBPALDH1A1HIF1AKMT2AMEN1
SCHEMBL4641633 0.81 CREBBP (0.40) CREBBPALDH1A1HIF1AKMT2AMEN1
SCHEMBL4642357 0.81 KDM4E (0.51) ALDH1A1KDM4ETDP1
SCHEMBL4641637 0.81 TSHR (0.50) CREBBPALDH1A1KMT2AMEN1KDM4E
SCHEMBL4644287 0.80 PTGDR2 (0.55) ALDH1A1KMT2AMEN1KDM4EPOLB
SCHEMBL4647759 0.77 ALDH1A1 (0.52) ALDH1A1KMT2AMEN1KDM4EMAPT
SCHEMBL4641834 0.77 TDP1 (0.41) CREBBPALDH1A1HIF1AKMT2AMEN1
SCHEMBL4644728 0.76 CREBBP (0.42) CREBBPALDH1A1HIF1AKMT2AMEN1
SCHEMBL1706804 0.76 ALDH1A1 (0.51) CREBBPALDH1A1KMT2AMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed