SCHEMBL4644463

SCHEMBL4644463

COC(=O)/C=C\C(=O)OCC(=O)Oc1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.48
ALDH1A1 P00352 7/20 0.48
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
KDM4E B2RXH2 1/20 0.39
PKM P14618 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
LMNA P02545 2/20 0.38
POLB P06746 1/20 0.38
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
GAA P10253 2/20 0.37
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642569 1.00 MAPT (0.48) MAPTALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL4642565 1.00 MAPT (0.48) MAPTALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL4642059 0.77 ALDH1A1 (0.40) MAPTALDH1A1MEN1KMT2APKM
SCHEMBL4642064 0.77 ALDH1A1 (0.40) MAPTALDH1A1MEN1KMT2APKM
SCHEMBL4644343 0.77 ALDH1A1 (0.40) MAPTALDH1A1MEN1KMT2APKM
SCHEMBL348786 0.74 CA1 (0.41) MAPTALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL27957060 0.74 KMT2A (0.44) MAPTALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL4646044 0.74 MAPT (0.44) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL4642362 0.74 MAPT (0.44) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL4642366 0.74 MAPT (0.44) MAPTALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed