Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14305007 | 0.91 | RAPGEF4 (0.41) | ALDH1A1KDM4EGAAMAPTTSHR | |
| SCHEMBL14311187 | 0.91 | CA1 (0.35) | CA1CA2CA9ALDH1A1KDM4E | |
| SCHEMBL8525341 | 0.90 | TDP1 (0.40) | CA1CA2CA9ALDH1A1KDM4E | |
| SCHEMBL14554131 | 0.89 | KDM4E (0.47) | ALDH1A1KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL4642299 | 0.85 | ALDH1A1 (0.41) | CA1CA2CA9ALDH1A1KDM4E | |
| SCHEMBL4642241 | 0.85 | CA1 (0.39) | CA1CA2CA9ALDH1A1KDM4E | |
| SCHEMBL4641646 | 0.83 | CA1 (0.38) | CA1CA2CA9ALDH1A1KDM4E | |
| SCHEMBL10981786 | 0.82 | CYP1A2 (0.45) | CA1CA2CA9ALDH1A1KDM4E | |
| SCHEMBL4642147 | 0.82 | CA1 (0.37) | CA1CA2CA9ALDH1A1KDM4E | |
| SCHEMBL4642224 | 0.82 | VCAM1 (0.40) | CA1CA2CA9ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684309-A | Near infrared frequency up-conversion fluorescent probe, benzopyrylium salt compound and preparation method and application thereof | 安徽大学 | 2025-03-25 | — | — | CN | claimed |
| CN-112939970-A | Pyridopyrimidinone derivative, preparation method thereof and application thereof in antitumor drugs | 林剑雄 | 2021-06-11 | — | — | CN | claimed |
| EP-1751122-B1 | MONOMER 5,6-DIPHENYL-1,2,4-TRIAZINIC DERIVATIVES AND THE USE THEREOF | FABRE PIERRE DERMO COSMETIQUE (FR) | 2010-03-17 | — | — | EP | claimed |
| US-20080299055-A1 | Monomer 5, 6-Diphenyl-1.2.4-Traizinic Derivatives and the Use Thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2008-12-04 | — | — | US | claimed |
| US-20260132129-A1 | 4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE DERIVATIVES FOR TREATING CANCER | GENESIS THERAPEUTICS INC (US) | 2026-05-14 | — | — | US | disclosed |
| US-20260078120-A1 | SUBSTITUTED PYRIDOPYRIMIDINONES | Mirati Therapeutics, Inc. (US) | 2026-03-19 | — | — | US | disclosed |
| US-20260055099-A1 | PROTACS FOR TARGETED DEGRADATION OF KAT2A AND KAT2B FOR THE TREATMENT OF CANCER | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2026-02-26 | — | — | US | disclosed |
| WO-2025233837-A1 | 4H-PYRIMIDO[1,2-A]PYRIMIDIN-4-ONE DERIVATIVES FOR USE AS NLRP3 INFLAMMASOME INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDER | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-11-13 | — | — | WO | disclosed |
| EP-4602043-A1 | 4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE DERIVATIVES FOR TREATING CANCER | Genesis Therapeutics, Inc. (US) | 2025-08-20 | — | — | EP | disclosed |
| EP-4577544-A1 | SUBSTITUTED PYRIDOPYRIMIDINONES | Mirati Therapeutics, Inc. (US) | 2025-07-02 | — | — | EP | disclosed |
| CN-119684309-B | Near infrared frequency up-conversion fluorescent probe, benzopyrylium salt compound and preparation method and application thereof | 安徽大学 | 2025-06-17 | — | — | CN | disclosed |
| US-20250188074-A1 | PTPN11 INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2025-06-12 | — | — | US | disclosed |
| EP-0159707-B1 | TRIAZOLOPYRIMIDINE DERIVATIVES | DAIICHI SEIYAKU CO., LTD. (JP) | 1990-01-24 | — | — | EP | disclosed |
| US-4866064-A | AGRICULTURE HORTICULTURE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0282635-A2 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |
| EP-0279298-A1 | Tricyclic triazolopyrimidine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |
| EP-0242690-A2 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-10-28 | — | — | EP | disclosed |
| EP-0238059-A2 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-23 | — | — | EP | disclosed |
| US-4652646-A | ANTIALLERGENS | DAIICHI SEIYAKU CO., LTD. (JP) | 1987-03-24 | — | — | US | disclosed |
| EP-0159707-A2 | Triazolopyrimidine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1985-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250188074-A1 | PTPN11 INHIBITORS | PTPRJ, PTPN11, PTPRF | CA1 4817/4885CA2 3899/4885CA9 4253/4885 |
| US-20080299055-A1 | Monomer 5, 6-Diphenyl-1.2.4-Traizinic Derivatives and the Use Thereof | POT1, TELO2, CLIC1 | CA1 1532/4885CA2 674/4885CA9 1033/4885 |
| US-20260132129-A1 | 4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE DERIVATIVES FOR TREATING CANCER | PIK3R4, PIK3R1, PIK3R5 | CA1 3844/4885CA2 2506/4885CA9 1720/4885 |
| US-20260055099-A1 | PROTACS FOR TARGETED DEGRADATION OF KAT2A AND KAT2B FOR THE TREATMENT OF CANCER | KAT2A, KAT2B, KAT8 | CA1 1959/4885CA2 3117/4885CA9 2033/4885 |
| US-20260078120-A1 | SUBSTITUTED PYRIDOPYRIMIDINONES | CBR1, CBR3, CNR1 | CA1 2773/4885CA2 1276/4885CA9 1563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.