Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640792 | 0.84 | CYP19A1 (0.39) | ABCC8KCNJ11NAMPTKDM4EMAPT | |
| SCHEMBL4642176 | 0.76 | NAMPT (0.37) | NAMPTKDM4ETP53 | |
| SCHEMBL2355400 | 0.72 | CYP19A1 (0.46) | GABRA1GABRG2GABRB3 | |
| SCHEMBL2355399 | 0.72 | CYP19A1 (0.46) | GABRA1GABRG2GABRB3 | |
| SCHEMBL2355395 | 0.72 | CYP19A1 (0.46) | GABRA1GABRG2GABRB3 | |
| SCHEMBL5091768 | 0.70 | GSK3B (0.49) | RAB9AKDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL11137590 | 0.69 | NPC1 (0.51) | NPC1RAB9AGABRA1GABRG2GABRB3 | |
| SCHEMBL5091485 | 0.64 | ALDH1A1 (0.51) | NPC1RAB9AKDM4EMAPTMAPK1 | |
| SCHEMBL3466767 | 0.64 | GABRA1 (0.45) | NPC1RAB9AGABRA1GABRG2GABRB3 | |
| SCHEMBL3466769 | 0.64 | GABRA1 (0.45) | NPC1RAB9AGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1804805-A4 | USE OF AROMATASE INHIBITORS FOR THE TREATMENT OF ECTOPIC PREGNANCY | UNIV WAYNE STATE (US) | 2008-08-13 | — | — | EP | disclosed |
| EP-1804805-A2 | USE OF AROMATASE INHIBITORS FOR THE TREATMENT OF ECTOPIC PREGNANCY | WAYNE STATE UNIVERSITY (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006041941-A2 | USE OF AROMATASE INHIBITORS FOR THE TREATMENT OF ECTOPIC PREGNANCY | WAYNE STATE UNIVERSITY (US) | 2006-04-20 | — | — | WO | disclosed |