SCHEMBL4644929

SCHEMBL4644929

COC(=O)/C=C/C(=O)OCCCC(=O)Oc1ccc(OC)cc1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.49
KMT2A Q03164 3/20 0.49
HSD17B10 Q99714 2/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPT P10636 1/20 0.49
HTT P42858 1/20 0.49
EGFR P00533 2/20 0.48
ERBB2 P04626 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
MEN1 O00255 1/20 0.46
TDP1 Q9NUW8 2/20 0.45
ATM Q13315 1/20 0.44
GAA P10253 1/20 0.41
GSK3B P49841 1/20 0.41
HPGD P15428 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642143 1.00 LMNA (0.49) LMNAKMT2AHSD17B10ALDH1A1MAPT
SCHEMBL4642153 1.00 LMNA (0.49) LMNAKMT2AHSD17B10ALDH1A1MAPT
SCHEMBL4641896 0.92 LMNA (0.51) LMNAKMT2AHSD17B10ALDH1A1MAPT
SCHEMBL4643971 0.92 LMNA (0.51) LMNAKMT2AHSD17B10ALDH1A1MAPT
SCHEMBL4641909 0.92 LMNA (0.51) LMNAKMT2AHSD17B10ALDH1A1MAPT
SCHEMBL4641955 0.90 LMNA (0.47) LMNAKMT2AHSD17B10ALDH1A1MAPT
SCHEMBL4644861 0.90 LMNA (0.47) LMNAKMT2AHSD17B10ALDH1A1MAPT
SCHEMBL4641969 0.90 LMNA (0.47) LMNAKMT2AHSD17B10ALDH1A1MAPT
SCHEMBL4643311 0.90 LMNA (0.47) LMNAKMT2AHSD17B10ALDH1A1MAPT
SCHEMBL4643303 0.90 LMNA (0.47) LMNAKMT2AHSD17B10ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed