SCHEMBL4641909

SCHEMBL4641909

COC(=O)C=CC(=O)OCCC(=O)Oc1ccc(OC)cc1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.51
KMT2A Q03164 4/20 0.51
HSD17B10 Q99714 2/20 0.51
MAPT P10636 2/20 0.51
ALDH1A1 P00352 2/20 0.51
HTT P42858 2/20 0.51
TDP1 Q9NUW8 1/20 0.47
MEN1 O00255 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
EGFR P00533 1/20 0.44
ERBB2 P04626 1/20 0.44
GAA P10253 2/20 0.43
GSK3B P49841 1/20 0.43
RECQL P46063 1/20 0.40
MAOB P27338 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4641896 1.00 LMNA (0.51) LMNAKMT2AHSD17B10MAPTALDH1A1
SCHEMBL4643971 1.00 LMNA (0.51) LMNAKMT2AHSD17B10MAPTALDH1A1
SCHEMBL4642143 0.92 LMNA (0.49) LMNAKMT2AHSD17B10MAPTALDH1A1
SCHEMBL4642153 0.92 LMNA (0.49) LMNAKMT2AHSD17B10MAPTALDH1A1
SCHEMBL4644929 0.92 LMNA (0.49) LMNAKMT2AHSD17B10MAPTALDH1A1
SCHEMBL4641851 0.89 KMT2A (0.49) LMNAKMT2AHSD17B10MAPTALDH1A1
SCHEMBL4642433 0.89 KMT2A (0.49) LMNAKMT2AHSD17B10MAPTALDH1A1
SCHEMBL4641841 0.89 KMT2A (0.49) LMNAKMT2AHSD17B10MAPTALDH1A1
SCHEMBL4643498 0.85 GAA (0.53) LMNAKMT2AHSD17B10MAPTALDH1A1
SCHEMBL4643506 0.85 GAA (0.53) LMNAKMT2AHSD17B10MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed