Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4645412 | 1.00 | TDP1 (0.40) | TDP1ALOX15LMNAMAPTMDM4 | |
| SCHEMBL4642383 | 0.88 | KLK7 (0.40) | TDP1LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL4646915 | 0.88 | KLK7 (0.40) | TDP1LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL4647206 | 0.86 | MAPT (0.52) | LMNAMAPTMDM4MDM2ALDH1A1 | |
| SCHEMBL4645338 | 0.86 | MAPT (0.52) | LMNAMAPTMDM4MDM2ALDH1A1 | |
| SCHEMBL4644973 | 0.81 | CA12 (0.41) | TDP1LMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL4645072 | 0.75 | HCAR2 (0.47) | TDP1LMNAMAPTMDM4MDM2 | |
| SCHEMBL4647771 | 0.75 | HCAR2 (0.47) | TDP1LMNAMAPTMDM4MDM2 | |
| SCHEMBL9392635 | 0.74 | TDP1 (0.45) | TDP1ALOX15LMNAMAPTMDM4 | |
| SCHEMBL9392641 | 0.74 | TDP1 (0.45) | TDP1ALOX15LMNAMAPTMDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487928-B1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2008-08-13 | — | — | EP | disclosed |
| EP-1487928-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | Jotun AS (NO) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080747-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2003-10-02 | — | — | WO | disclosed |