SCHEMBL4644973

SCHEMBL4644973

CCOC(=O)C=CC(=O)OC(C(=O)OC(C)=O)C(=O)c1ccc(OC)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
MAOB P27338 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C19 P33261 1/20 0.40
HDAC3 O15379 2/20 0.40
HDAC4 P56524 2/20 0.40
HDAC1 Q13547 2/20 0.40
HDAC7 Q8WUI4 2/20 0.40
HDAC2 Q92769 2/20 0.40
HDAC10 Q969S8 2/20 0.40
HDAC11 Q96DB2 2/20 0.40
HDAC8 Q9BY41 2/20 0.40
HDAC6 Q9UBN7 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642392 0.89 SLC2A1 (0.40) CA12CA1CA2CA9MEN1
SCHEMBL4645346 0.86 MAPT (0.46) CA12CA1CA2CA9MEN1
SCHEMBL4644962 0.81 TDP1 (0.40) CA12CA1CA2CA9MAOB
SCHEMBL4645412 0.81 TDP1 (0.40) CA12CA1CA2CA9MAOB
SCHEMBL4645080 0.76 ALDH1A1 (0.42) CA12CA1CA2CA9MEN1
SCHEMBL29098731 0.75 MAPT (0.59) MAOBMEN1KMT2ACYP1A2CYP3A4
SCHEMBL9578915 0.75 MAPT (0.59) MAOBMEN1KMT2ACYP1A2CYP3A4
SCHEMBL4641762 0.74 HCAR2 (0.44) CA12CA1CA2CA9MAPT
SCHEMBL4644392 0.72 MAPT (0.44) CA12CA1CA2CA9MEN1
SCHEMBL4644572 0.72 MAPT (0.46) MEN1KMT2AMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed