SCHEMBL4645267

SCHEMBL4645267

C[CH]C(=O)OC(=O)COc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.53
MAPT P10636 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
ALDH1A1 P00352 1/20 0.44
RAB9A P51151 2/20 0.44
NPC1 O15118 1/20 0.44
AOC2 O75106 2/20 0.44
MAOA P21397 2/20 0.44
MAOB P27338 2/20 0.44
ALPL P05186 1/20 0.44
ALPI P09923 1/20 0.44
ALPG P10696 1/20 0.44
DAO P14920 1/20 0.44
HTT P42858 2/20 0.43
GLA P06280 1/20 0.43
GAA P10253 1/20 0.43
HPGD P15428 1/20 0.42
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4645866 0.83 MAPT (0.48) MAPTSMN1; SMN2KMT2AMEN1ALDH1A1
SCHEMBL4644545 0.83 ALOX15 (0.50) ALOX15MAPTSMN1; SMN2KMT2AMEN1
SCHEMBL264346 0.83 ALOX15 (0.68) ALOX15MAPTSMN1; SMN2KMT2AMEN1
SCHEMBL4643925 0.81 ALOX15 (0.47) ALOX15MAPTSMN1; SMN2KMT2AMEN1
SCHEMBL9602821 0.80 ALOX15 (0.59) ALOX15MAPTSMN1; SMN2KMT2AMEN1
SCHEMBL264347 0.80 ALOX15 (0.59) ALOX15MAPTSMN1; SMN2KMT2AMEN1
SCHEMBL27718339 0.80 ALOX15 (0.63) ALOX15MAPTSMN1; SMN2KMT2AMEN1
SCHEMBL27502591 0.79 RAB9A (0.51) ALOX15MAPTSMN1; SMN2KMT2AMEN1
SCHEMBL8903465 0.79 ALOX15 (0.57) ALOX15MAPTSMN1; SMN2KMT2AMEN1
Acetonitrile SCHEMBL23706321 0.77 ALOX15 (0.55) ALOX15MAPTSMN1; SMN2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed