Sugi Predict

Sugi Predict / Compounds / SCHEMBL4645276

SCHEMBL4645276

SCHEMBL4645276

C[Si](C)(C)OC(=O)CCCCl

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.37
▸ ALDH1A1 P00352 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ DGKA P23743 1/20 0.30
▸ CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4645583 0.93 TSHR (0.36) TSHRALDH1A1DGKA
SCHEMBL4644909 0.86 TSHR (0.32) TSHR
SCHEMBL10739007 0.85 TSHR (0.50) TSHRALDH1A1DGKACYP1A2
SCHEMBL134075 0.85 TSHR (0.43) TSHRALDH1A1DGKACYP1A2
SCHEMBL8463255 0.83 DGKA (0.43) TSHRALDH1A1DGKA
SCHEMBL16295140 0.83 DGKA (0.43) TSHRALDH1A1DGKA
SCHEMBL8465959 0.83 DGKA (0.43) TSHRALDH1A1DGKA
SCHEMBL8463526 0.83 DGKA (0.43) TSHRALDH1A1DGKA
SCHEMBL4641699 0.81 TSHR (0.38) TSHRALDH1A1DGKACYP1A2
SCHEMBL4303758 0.80 TSHR (0.45) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 — — EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 — — EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 — — WO disclosed