SCHEMBL8463255

SCHEMBL8463255

C[Si](C)(C)OC(=O)CCCCCCCCCCC(=O)O[Si](C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.43
TSHR P16473 4/20 0.42
LMNA P02545 5/20 0.40
PAM P19021 2/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.38
MAPK1 P28482 1/20 0.38
DNM1 Q05193 1/20 0.35
NAAA Q02083 1/20 0.35
NFKB1 P19838 1/20 0.35
PMP22 Q01453 1/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8465959 1.00 DGKA (0.43) DGKATSHRLMNAPAMALDH1A1
SCHEMBL16295140 1.00 DGKA (0.43) DGKATSHRLMNAPAMALDH1A1
SCHEMBL8463526 1.00 DGKA (0.43) DGKATSHRLMNAPAMALDH1A1
SCHEMBL134075 0.97 TSHR (0.43) DGKATSHRLMNAPAMALDH1A1
SCHEMBL10739007 0.92 TSHR (0.50) DGKATSHRLMNAPAMALDH1A1
SCHEMBL155828 0.91 DGKA (0.57) DGKATSHRLMNAPAMALDH1A1
SCHEMBL9436470 0.91 DGKA (0.57) DGKATSHRLMNAPAMALDH1A1
SCHEMBL2701285 0.91 DGKA (0.57) DGKATSHRLMNAPAMALDH1A1
SCHEMBL17578973 0.91 DGKA (0.57) DGKATSHRLMNAPAMALDH1A1
SCHEMBL6554418 0.91 DGKA (0.57) DGKATSHRLMNAPAMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0909301-A1 BIODEGRADABLE LIQUID CRYSTALLINE POLYMERS Smith & Nephew plc (GB) 1999-04-21 EP disclosed
WO-1997048782-A1 BIODEGRADABLE LIQUID CRYSTALLINE POLYMERS SMITH & NEPHEW PLC (GB) 1997-12-24 WO disclosed