SCHEMBL4645277

SCHEMBL4645277

C=C(C)C(=O)OCCOCCOCCCCOCC(C)C

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.59
THRB P10828 1/20 0.56
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 5/20 0.36
PLA2G2C Q5R387 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
HSD17B10 Q99714 1/20 0.32
SPHK2 Q9NRA0 1/20 0.32
SPHK1 Q9NYA1 1/20 0.32
CES2 O00748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7628509 0.95 TSHR (0.66) TSHRTHRBPOLBAPEX1HTT
SCHEMBL10579270 0.95 TSHR (0.66) TSHRTHRBPOLBAPEX1HTT
SCHEMBL4644631 0.93 TSHR (0.68) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11213009 0.90 TSHR (0.63) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1991763 0.88 THRB (0.70) TSHRTHRBPOLBAPEX1HTT
SCHEMBL14706828 0.86 THRB (0.68) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9464153 0.86 THRB (0.68) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1818904 0.85 THRB (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9568827 0.84 THRB (0.70) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2742411 0.84 THRB (0.70) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111533854-B Silicon modified acrylic resin and application thereof 上海亿祺化工技术有限公司 2023-03-31 CN disclosed
CN-111533854-A Silicon modified acrylic resin and application thereof 上海亿祺化工技术有限公司 2020-08-14 CN disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed